武汉市春秋季室外不同粒径颗粒物暴露对大学生1秒用力呼气量的急性影响

发布时间：2018-02-09 04:10

本文关键词： 大气颗粒物肺功能急性影响大学生　出处：《环境与健康杂志》2015年03期 　论文类型：期刊论文

【摘要】：目的研究春、秋季室外颗粒物PM10、PM2.5及PM2.5-10的短期暴露对大学生肺功能1秒用力呼气量(FEV1)的影响。方法选取武汉市某大学2年级37名学生作为研究对象,采用固定群组追踪研究的方法,于2009年秋季(10月29日—11月11日,连续14 d)和2010年春季(3月24日—4月6日,连续14 d)两个时段内分别测定其早、晚FEV1,同时监测室外PM10、PM2.5浓度和温湿度变化。构建广义估计方程定量评价颗粒物暴露对学生FEV1的影响。结果春季PM10、PM2.5和PM2.5-10浓度每升高10μg/m3时,当晚FEV1分别下降0.20%(β的95%CI:-0.37%~-0.04%),0.48%(β的95%CI:-0.88%~-0.07%)和0.29%(β的95%CI:-0.53%~-0.04%),差异有统计学意义(P0.05),但其滞后和累积效应无统计学意义(P0.05)。秋季大气颗粒物的暴露与晚上FEV1无统计学关联(P0.05),PM2.5-10浓度每升高10μg/m3时,滞后3 d的早上FEV1下降0.41%(95%CI:-0.81%~0.00%),差异有统计学意义(P0.05)。结论武汉市春、秋季室外颗粒物的短期暴露对大学生FEV1存在急性影响,其中PM2.5-10暴露对肺功能的影响亦应引起重视。
[Abstract]:Objective to study the effects of outdoor particulate matter (PM10) PM2.5 and PM2.5-10 on forced expiratory volume (FEV1) of college students at 1 seconds in spring and autumn. Methods 37 sophomores in a university in Wuhan were selected as subjects. Using the method of fixed group tracking, the morning was measured in the autumn (October 29th-November 11th, 14 days) and the spring (March 24th-March 24th, 14 days) in the autumn, respectively, during the period of October 29th to November 11th, and in the spring of March 24th to March 24th for 14 consecutive days, respectively. The changes of PM2.5 concentration and temperature and humidity were monitored at the same time. A generalized estimation equation was established to quantitatively evaluate the effect of particulate matter exposure on FEV1 of students. Results when PM10P PM2.5 and PM2.5-10 concentrations increased by 10 渭 g / m ~ 3 in spring, The FEV1 fell 0.20% (95CI: -0.37-0.04) and 0.48 (95CI-0.88-0.07) and 0.29 (95CI: -0.53- 0.04), respectively. The difference was statistically significant (P0.055.But the lag and cumulative effects were not statistically significant (P0.055.There was no statistical correlation between the exposure of atmospheric particulates in autumn and the evening FEV1). When the concentration of PM2.5-10 increased by 10 渭 g / m3, there was no statistical correlation between the exposure of atmospheric particulates in autumn and the concentration of PM2.5-10 in the evening, when the concentration of PM2.5-10 was increased by 10 渭 g / m3, and there was no statistical correlation between the exposure of atmospheric particulates in autumn and the concentration of PM2.5-10 in the evening. In the morning, FEV1 decreased by 0.41% -0.81%, and the difference was statistically significant (P 0.05). Conclusion Short-term exposure of outdoor particulate matter in spring and autumn in Wuhan has an acute effect on FEV1 of college students, among which, the effect of PM2.5-10 exposure on lung function should be paid more attention.
【作者单位】：武汉大学公共卫生学院流行病与卫生统计学系;日本国立环境研究所环境健康研究综合影响评价研究室;日本兵库医科大学公共卫生学系;
【基金】：湖北省卫计委一般项目(JX6B59)
【分类号】：X513;R122

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