2008-2016年非洲亚撒哈拉地区HPV疫苗免疫项目的策略与成效分析

发布时间：2018-02-23 22:28

本文关键词： 人乳头瘤病毒疫苗接种交付模型非洲亚撒哈拉地区　出处：《现代预防医学》2017年19期 　论文类型：期刊论文

【摘要】：目的分析非洲亚撒哈拉地区在2008-2016年期间开展的HPV疫苗免疫项目策略及成效,为合理的设计和实施HPV疫苗免疫项目提供依据。方法检索与非洲亚撒哈拉地区HPV疫苗免疫项目相关的文献、基金申请、项目报告、新闻报道等资料,从基础保障能力、项目可及能力与持续能力、项目成效三方面提取指标信息,进行分析。结果在2008-2016年间,非洲亚撒哈拉地区有27个国家共开展了45个HPV疫苗免疫项目。大部分项目采用年龄靶向策略(n=23,51.11%),其次是年级靶向策略(n=18,40%)。采用学校交付模型的项目较多(n=27,64.44%),其次是综合交付模型(n=11,24.44%)、卫生机构交付模型(n=5,11.11%)和结合活动交付模型(n=2,4.44%)。疫苗接种率(VUR)平均值为84.55%(SD=13.03,n=14);全剂依从率(VAR)的平均值为91.13%(SD=4.44,n=11)。官方机构统筹项目的 VUR高于民间机构(92.73%vs 86.86%,P=0.048)。结论在非洲亚撒哈拉地区实施的HPV疫苗免疫项目取得了较理想的效果。有针对性的设计和实施策略是保证HPV疫苗免疫项目成效的关键。
[Abstract]:Objective to analyze the HPV vaccine project strategies and results in sub Saharan Africa during 2008-2016 years, and provide a reasonable basis for the design and implementation of HPV vaccine. Methods to retrieve related project HPV vaccine in sub Saharan Africa literature, fund application, project reports, news reports and other information, from the fundamental capacity the project, and ability and sustainable ability, the project effect three aspects extraction index information were analyzed. Results in 2008-2016 years, sub Saharan Africa has 27 countries launched a total of 45 HPV vaccine project. Most of the projects by age targeting strategy (n=23,51.11%), is the second grade targeting strategy (n=18,40%) the school. Delivery model more projects (n=27,64.44%), followed by the integrated delivery model (n=11,24.44%), health institutions (n=5,11.11%) and delivery model (n model combined with the delivery activities =2,4.44%). Vaccination rate (VUR) with an average of 84.55% (SD=13.03, n=14); the agent compliance rate (VAR) of the average value of 91.13% (SD=4.44, n=11). The VUR is higher than the official institutions to co-ordinate the project of non-governmental organizations (92.73%vs 86.86%, P=0.048). HPV vaccine project implementation in sub Saharan Africa to conclusion the ideal effect is obtained. The design and implementation of the strategy is the key to ensure the effectiveness of the HPV vaccine project.

【作者单位】：中山大学公共卫生学院医学统计与流行病学系;中山大学全球卫生研究中心;中山大学孙逸仙纪念医院;
【分类号】：R186

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