天津市流行性腮腺炎疫苗纳入免疫规划效果评价

发布时间：2018-02-27 14:56

本文关键词： 流行性腮腺炎麻疹、流行性腮腺炎和风疹联合疫苗流行特征抗体阳性率　出处：《现代预防医学》2016年11期 　论文类型：期刊论文

【摘要】：目的麻疹、流行性腮腺炎和风疹联合疫苗纳入天津市免疫规划后,对流行性腮腺炎的控制效果进行评价。方法利用全国传染病报告管理系统和天津市流行性腮腺炎专报平台数据分析疾病流行特征和免疫状况,开展血清学监测评价人群抗体水平。结果 2007-2014年天津市流行性腮腺炎发病率从40.34/10万下降到11.14/10万,0~4岁组病例比例从9.50%增加到32.50%,10~14岁组从33.20%降低到12.93%,5~9岁和10-14岁组发病率降幅分别为70.41%和81.05%。2013-2014年共调查10岁组流行性腮腺炎病例2 195例,个案调查率分别是83.45%和96.78%,病例中87.19%有至少1剂次免疫史。其中18月龄~2岁85.85%有1剂次疫苗免疫史,在3~4岁组中达到91.33%,5-9岁组有73.81%的病例有≥2剂次免疫史。2007-2014年天津市开展了4次健康人群流行性腮腺炎IgG抗体监测,抗体阳性率分别是2007年73.52%、2011年74.09%、2013年74.04%和2014年79.85%,经χ2检验,各年份抗体阳性率无统计学差异(χ~2=6.51,P=0.09)。不同年龄组中,18月龄~2岁、3~4岁和5~9岁组抗体阳性率近年来逐渐升高,其中2014年3~4岁和5~9岁组抗体阳性率分别达到91.53%和98.33%。结论加强流行性腮腺炎监测和实现消除目标,应提高病例实验室检测率和开展2剂次MMR疫苗接种。
[Abstract]:Objective to incorporate measles, mumps and rubella vaccine into Tianjin immunization program, Methods the epidemic characteristics and immune status of mumps were analyzed by using the data of national infectious disease report management system and Tianjin mumps report platform. Results from 2007 to 2014, the incidence of mumps in Tianjin decreased from 40.34% to 111.4% and increased from 9.50% to 32.50% 1014 years old from 33.20% to 12.933% and 10-14 years old. The decrease was 70.41% and 81.05 respectively. A total of 2,195 mumps cases were investigated in the 10-year-old group in 2013-2014. The investigation rates were 83.45% and 96.78, respectively. 87.19% of the cases had at least one dose of immunization history. 73.81% cases of patients aged 5 to 9 in the group of 3 or 4 years of age had more than 2 doses of immunization. From 2007 to 2014, four times of surveillance of IgG antibody against mumps were carried out in Tianjin. The positive rates of antibody were 73.52% on 2007, 74.09% on 2011, 74.04% on 2013 and 79.85% on 2013, respectively, with 蠂 2 test, the positive rate of antibody was 73.52% on 2007, 74.09% on 2011, 79.85% on 2013 74.04%, and 79.85% on 2013 on 2013. There was no significant difference in the positive rates of antibodies between different years (蠂 2 / 6.51 / P 0.09). The positive rates of antibodies in the groups of 18 months old or 2 years old or 3 years old and 5 years old were gradually increased in recent years. In 2014, the antibody positive rates of 3 and 9 years old group reached 91.53% and 98.33 respectively. Conclusion to strengthen the surveillance of mumps and achieve the goal of elimination, we should increase the rate of case laboratory detection and carry out two doses of MMR vaccination.
【作者单位】：天津市疾病预防控制中心;
【分类号】：R186.2

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