保定市COXA6型手足口病伴脱甲症病例流行病学特征及相关因素分析

发布时间：2018-03-03 22:09

  本文选题：柯萨奇肠道病毒A　切入点：手足口病　出处：《现代预防医学》2017年05期 　论文类型：期刊论文

【摘要】：目的了解保定市COXA6型手足口病伴脱甲症病例的流行病学特征及相关因素,为制定防控措施提供科学依据。方法采用荧光定量RT-PCR法对2015年1月至2016年5月保定市哨点医院采集的手足口病病例咽拭子标本进行柯萨奇病毒A6型核酸检测,筛选COXA6型手足口病,并按是否伴有脱甲分为脱甲组和未脱甲组,利用检验对两组人群分布、临床特征、皮损特征及卫生行为情况进行对比分析,并利用Logistic回归分析COXA6型手足口病伴脱甲症的相关因素。结果保定市COXA6型手足口病伴脱甲症病例主要集中在5岁以内,以1~2岁患儿所占比例最高且男性多于女性。既往有皮肤过敏史(OR=5.230)、皮疹在指或趾甲周围分布(OR=10.599)和皮疹面积大于5%(OR=10.776)为COXA6型手足口病伴脱甲症病例的危险因素。结论对于既往有皮肤过敏史、皮疹在指或趾甲周围分布以及皮疹面积大于5%的COXA6型手足口病患儿要加强重视,以防其脱甲症的发生。同时在COXA6型手足口病流行期间加强的卫生防范措施,不会导致脱甲症的发生。
[Abstract]:Objective to investigate the epidemiological characteristics and related factors of COXA6's hand, foot and mouth disease with dethyroidism in Baoding City. Methods the throat swabs of hand-foot-mouth disease cases collected from January 2015 to May 2016 in Baoding City were detected by fluorescence quantitative RT-PCR method for Coxsackie virus A6 nucleic acid. COXA6 type hand-foot-mouth disease was screened and divided into two groups according to whether it was accompanied by de-armor or not. The distribution, clinical characteristics, skin lesions and hygienic behavior of the two groups were compared and analyzed by means of test. Logistic regression analysis was used to analyze the related factors of COXA6 hand, foot and mouth disease with dethyroidism. Results the cases of COXA6 hand foot and mouth disease with dethyroidism in Baoding City were mainly within 5 years old. The proportion of children aged 1 to 2 years was the highest and the proportion of males was higher than that of females. The history of skin allergy was 5.230%, and the skin rash was distributed around the fingers or toenails. (10.599) and the area of rash was larger than 50.776) as the risk factors of COXA6 hand, foot and mouth disease with dethyroidism. Had a history of skin allergies, Attention should be paid to the distribution of skin rash around finger or toenail and the area of skin rash larger than 5% in children with hand, foot and mouth disease of COXA6 type, so as to prevent the occurrence of dethyroidism. Meanwhile, the health precautions should be strengthened during the epidemic period of COXA6 hand, foot and mouth disease. It does not cause dethyroidism.
【作者单位】： 保定市疾病预防控制中心;唐县人民医院;保定市第一中医院;
【基金】：保定市科学技术研究与发展指导计划项目,项目编号为15ZF088
【分类号】：R725.1;R181.3
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本文编号：1562895