全麦粉对实验型糖尿病大鼠血糖控制效应的影响

发布时间：2018-03-05 10:44

本文选题：全麦粉　切入点：糖尿病　出处：《食品科技》2015年11期 　论文类型：期刊论文

【摘要】：目的:研究全麦粉对实验型糖尿病大鼠血糖、血红蛋白及肝糖原含量的影响。方法:将大鼠随机分为正常组、模型组、精粉组、全麦粉组,除正常组外,其他组用四氧嘧啶建立糖尿病大鼠模型;分别用标准饲料、高脂饲料、精粉饲料、全麦粉饲料喂养各组大鼠。喂养5周后,用葡萄糖氧化酶-过氧化物酶法测定血糖含量;酶联免疫吸附法(ELISA)测定血红蛋白含量;蒽酮比色法测定肝糖原含量。结果:喂养结束时,全麦粉组血糖水平由(18.64±2.86)mmol/L降低至(13.80±3.65)mmol/L,虽高于正常组(5.40±0.68)mmol/L的血糖水平,但与模型组与精粉组相比较明显降低;全麦粉组血红蛋白含量降至(20.69±0.37)mmol/L,低于模型组(30.95±0.51)mmol/L和精粉组(30.12±0.39)mmol/L的血红蛋白含量;全麦粉组的肝糖原含量为(12.50±0.23)mg/g低于正常组的含量(17.70±0.26)mg/g,但高于模型组和精粉组的(7.96±0.19)mmol/L和(8.90±0.31)mmol/L。结论:全麦粉可降低糖尿病大鼠血糖水平和血红蛋白含量,增加肝糖原含量,对糖尿病大鼠的血糖效应具有正向调节作用。
[Abstract]:Objective: to study the effect of whole wheat flour on blood glucose, hemoglobin and liver glycogen content in experimental diabetic rats. Methods: rats were randomly divided into normal group, model group, refined powder group, whole wheat flour group, except normal group. The diabetic rats in other groups were fed with standard diet, high fat diet, concentrate feed and whole wheat meal feed respectively. After 5 weeks of feeding, the blood glucose content was measured by glucose oxidase peroxidase method. Results: at the end of feeding, the blood glucose level of whole wheat flour group decreased from 18.64 卤2.86 mmol / L to 13.80 卤3.65 mmol / L, although it was higher than that of normal group (5.40 卤0.68 mmol / L). The hemoglobin content in the whole wheat flour group decreased to 20.69 卤0.37 mmol / L, which was lower than that in the model group (30.95 卤0.51g / L) and the refined powder group (30.12 卤0.39 mmol / L). The content of liver glycogen in the whole wheat flour group was 12.50 卤0.23 mg / g lower than that in the normal group (17.70 卤0.26 mg / g), but higher than that in the model group and the seminal powder group (7.96 卤0.19 mmol / L and 8.90 卤0.31 mmol / L). Conclusion: whole wheat meal can decrease the blood sugar level and hemoglobin content in diabetic rats and increase the hepatic glycogen content. It has positive regulation effect on blood glucose in diabetic rats.
【作者单位】：河南工业大学粮油食品学院;
【基金】：河南省高等学校重点科研项目(15A550002)
【分类号】：R151.1

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