有机和无机干扰物质对过氧化氢气体等离子体灭菌效果的影响

发布时间：2018-03-07 03:11

本文选题：过氧化氢气体等离子体　切入点：灭菌监测　出处：《中国消毒学杂志》2015年04期 　论文类型：期刊论文

【摘要】：目的研究有机物和无机干扰物对过氧化氢气体等离子体灭菌效果的影响。方法通过载体定性灭菌试验和灭菌效果验证装置测试法,对三种有机物和一种无机物对过氧化氢气体等离子体灭菌效果的影响进行了观察。结果有机物、氯化钠溶液和羊血污染的菌片,放置在表面对灭菌没有明显影响。不同测试物对管腔型器械灭菌效果的影响进行方差分析后发现,不同浓度小牛血清之间的差异无统计学意义;25%小牛血清白蛋白(BSA)与12%BSA、6%BSA之间的差异有统计学意义,而12%BSA和6%BSA组间差异无统计学意义。不同浓度氯化钠组各组两两之间的差异均有统计学意义。不同浓度羊血组各组两两之间的差异均有统计学意义。结论 BSA对灭菌的影响高于小牛血清。氯化钠溶液影响过氧化氢气体等离子体灭菌器对管腔类器械的灭菌效果,随着氯化钠浓度的提高对灭菌效果影响增大。稀释到1%的羊血也影响过氧化氢气体等离子体灭菌器对管腔类器械的灭菌效果,随着羊血浓度的提高对灭菌效果影响增大。
[Abstract]:Objective to study the effect of organic matter and inorganic interference on the sterilization effect of hydrogen peroxide gas plasma. The effects of three organic compounds and one inorganic substance on the sterilizing effect of hydrogen peroxide gas plasma were observed. Placing on the surface had no obvious effect on sterilization.The variance analysis of the effects of different test materials on sterilizing effect of tube type instruments showed that, There was no significant difference between different concentrations of calf serum (25% BSA) and 12 BSAs (6 BSA). However, there was no significant difference between BSA and 6BSA groups. There was significant difference between two groups in different concentrations of sodium chloride group, and significant difference between two groups in different concentrations of sheep blood group. Conclusion there is a significant difference between two groups in different concentrations of BSA. The effect of sodium chloride solution on the sterilizing effect of hydrogen peroxide gas plasma sterilizer was higher than that of calf serum. With the increase of the concentration of sodium chloride, the effect of sterilizing effect was increased. The effect of hydrogen peroxide gas plasma sterilizer on the sterilizing effect of tube cavity was also affected by the dilution of sheep blood to 1%, and the effect of sheep blood concentration on sterilizing effect increased with the increase of the concentration of sheep blood.
【作者单位】：中国疾病预防控制中心环境与健康相关产品安全所;
【分类号】：R187

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