孕妇血清维生素D水平与婴幼儿神经系统发育的临床观察

发布时间：2018-03-16 08:21

本文选题：孕妇　切入点：维生素D　出处：《重庆医学》2015年06期 　论文类型：期刊论文

【摘要】：目的探讨孕妇维生素D水平对婴幼儿神经系统发育的影响。方法对1 012名孕妇进行孕早期血清维生素D含量检测,将其分为维生素D正常组、不足组以及缺乏组;采用0~6岁儿童发育筛查测验(DST)对各组所生子女在6~8个月龄时的发育商(DQ)、智力指数(MI)等各项神经发育指标进行检测。结果 94.17%的孕妇在孕早期出现严重的维生素D缺乏情况,平均含量仅为(16.21±7.54)ng/mL;补充维生素D后孕晚期46.25%的孕妇出现维生素D缺乏;对各组孕妇所生育的1 020名婴幼儿神经发育考察,DQ平均(92.67±16.45)分,MI平均(97.53±17.04)分;其中,正常组孕妇的婴幼儿发育商优秀、聪明的比例均优于不足组及缺乏组,且差异均有统计学意义(P0.01)。维生素D水平与DQ呈正相关(r=0.63),与MI呈正相关,相关性较弱(r=0.2)。结论应重视对孕妇在孕期中维生素D水平的监测,对于缺乏者应及时补充。
[Abstract]:Objective to investigate the effect of vitamin D level on the development of nervous system in infants and children. Methods 1 012 pregnant women were divided into normal group, deficient group and deficient group. A developmental screening test (DST) was used to detect the developmental quotient (DQ) and intelligence index (MI) of the children born in each group at the age of 6 ~ 8 months. Results 94.17% of the pregnant women developed severe vitamin D deficiency in the first trimester of pregnancy. The average content of vitamin D was only 16.21 卤7.54 ng / mL; 46.25% pregnant women had vitamin D deficiency after vitamin D supplementation; the average MI score was 97.53 卤17.04 in 1 020 infants and children born in each group. The infant development quotient of normal pregnant women was excellent, the proportion of intelligence was better than that of deficiency group and deficiency group, and the difference was statistically significant (P 0.01). Vitamin D level was positively correlated with DQ, 0.63% and MI, respectively. Conclusion attention should be paid to the monitoring of vitamin D level in pregnant women, and should be replenished in time for those who lack it.
【作者单位】：重庆市荣昌县人民医院妇产科;重庆市荣昌县妇幼保健院儿科;
【分类号】：R174

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