2010-2013年呼和浩特市疑似预防接种异常反应监测分析

发布时间：2018-03-20 06:00

本文选题：疑似预防接种异常反应　切入点：监测　出处：《现代预防医学》2015年17期 　论文类型：期刊论文

【摘要】：目的分析呼和浩特市疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的发生特征,评价AEFI监测系统的运转情况及预防接种安全性。方法通过AEFI监测系统收集呼和浩特市2010-2013年AEFI监测系统报告的个案数据,采用描述性流行病学方法对相关指标进行分析。结果 2010-2013年呼和浩特市共报告AEFI病例326例,报告发生率为1.31/万;4岁病例占88.04%(287/326);男女性别比为1.22∶1;主要集中在9月份;AEFI分类中主要以不良反应为主,占报告总数的97.55%,偶合症占2.45%;无心因性等群体性预防接种异常反应、疫苗质量事故和接种事故;不良反应中以一般反应为主,占77.67%(247/318),异常反应报告71例,占22.33%(71/318);AEFI疫苗分布中以麻疹疫苗最常见,占27.61%,其次为无细胞百白破疫苗,占14.11%;83.13%AEFI反应发生在疫苗接种后1 d,临床损害以发热和红肿/硬结为主,占55.83%;全市9个旗县区均有AEFI数据报告,48h及时报告率为91.41%,48 h及时调查率为98.88%。结论监测数据表明,呼和浩特市AEFI监测系统总体运转情况正常,需进一步提高全市AEFI监测敏感性和质量。
[Abstract]:Objective to analyze the characteristics of the abnormal response to suspected vaccination in Hohhot, Adverse Events Following Immunization (AEFI). To evaluate the operation of AEFI monitoring system and the safety of vaccination. Methods the case data of AEFI monitoring system from 2010 to 2013 in Hohhot city were collected through AEFI monitoring system. Results A total of 326 AEFI cases were reported in Hohhot from 2010 to 2013. The reported incidence rate of 4 year old cases was 88.040.287 / 3260.The sex ratio of male to female was 1.22: 1.In September, the main adverse reactions in the classification of AEFI were 97.55% of the total reported cases, and the incidentals accounted for 2.45% of the total number of reported cases. The adverse reactions were mainly general reactions (77.67%), and 77.67% (247 / 318g) of AEFI vaccines. 71 cases of abnormal reactions were reported, accounting for 22.3371% (31.18%) of the distribution of AEFI vaccine. Measles vaccine was the most common vaccine, accounting for 27.61% of AEFI vaccine, followed by acellular white tetanus vaccine. Account for 14.11; 83.13FI reaction occurred 1 day after vaccination, the main clinical damage was fever and redness / sclerosis, accounting for 55.83.The AEFI data report for 48h was reported in 9 flag counties and districts of the whole city. The timely investigation rate of 91.41FI and 48h was 98.88. Conclusion Monitoring data shows that, The AEFI monitoring system in Hohhot is running normally, so the sensitivity and quality of AEFI monitoring should be further improved.
【作者单位】：呼和浩特市疾病预防与控制中心免疫规划科;
【分类号】：R186

【参考文献】