2013-2016年南京市疑似预防接种异常反应监测分析

发布时间：2018-03-25 01:40

本文选题：疑似预防接种异常反应　切入点：监测　出处：《现代预防医学》2017年23期

【摘要】：目的分析南京市2013-2016年疑似预防接种异常反应(AFEI)的发生特征,初步评价疑似预防接种异常反应监测系统运转情况和疫苗接种的安全性。方法通过AEFI信息管理系统,收集南京市2013-2016年报告的AEFI个案数据,采用描述流行病学方法进行分析。结果 2013-2016年南京市共报告AEFI 4 277例,报告覆盖率为100%,报告发生率为40.93例/10万剂。AEFI报告数男、女性别比为1.36∶1,2岁占74.40%(3 182/4 277)。AEFI报告例数居前五位的区分别是江宁区、浦口区、秦淮区、六合区和鼓楼区。I类疫苗AEFI共报告3 542例,占82.82%(3 542/4277),报告发生率为50.32例/10万剂,II类疫苗AEFI共报告735例,占17.18%(735/4 277),报告发生率为21.55例/10万剂。一般反应3 809例,占到89.06%(3 809/4 277),报告发生率为36.45例/10万剂,以发热、红肿、硬结为主;异常反应441例,占10.31%(441/4 277),报告发生率为4.22例/10万剂,以过敏性皮疹为主;接种疫苗后24h内出现反应3 671例,占85.83%(3 671/4 277);99.93%病例治愈或好转。结论南京市AEFI监测系统运行情况良好,AEFI主要发生于2岁儿童接种疫苗后24h内,为AEFI监测的重点。
[Abstract]:Objective to analyze the occurrence characteristics of suspected abnormal vaccination response (AFEI) from 2013 to 2016 in Nanjing, and to evaluate the operation of the abnormal reaction monitoring system and the safety of vaccination. Methods AEFI information management system was used. Data of AEFI cases reported from 2013 to 2016 in Nanjing were collected and analyzed by descriptive epidemiological method. Results A total of 4 277 cases of AEFI were reported in Nanjing from 2013 to 2016, with a reported coverage rate of 100 cases and a reported incidence rate of 40.93 cases / 100000 doses of AEFI. The female ratio of 1.36: 1 / 2 years old accounted for 3 542 cases of type I vaccine AEFI reported in Jiangning District, Pukou District, Qinhuai District, Liuhe District and Gulou District, respectively, in the area of 74.402 / 3 182 / 4 / 4 277).AEFI reported by Jiangning District, Pukou District, Qinhuai District, Liuhe District and Gulou District. The reported incidence rate was 50.32 cases / 100000 doses of class II vaccine AEFI, accounting for 17.18% 735% 4277%, the reported incidence rate was 21.55 cases / 100000 dose. General reaction 3 809 cases, 89.06% 3 809% 4 277%, the reported incidence rate was 36.45 cases / 100000 dose. There were 441 cases of abnormal reaction, accounting for 10.31% of 441R / 4277g, the reported incidence rate was 4.22 cases / 100000 dose, mainly allergic rash, and 3 671 cases of reaction occurred within 24 hours after vaccination. 99.93% of the cases were cured or improved. Conclusion the AEFI monitoring system in Nanjing is mainly occurred within 24 hours after inoculation of 2 year old children, which is the key point of AEFI monitoring.
【作者单位】：南京市疾病预防控制中心免疫规划科;
【分类号】：R186

【相似文献】