不同环境下复方柳叶熏蒸消毒剂的消毒效果及安全性评价

发布时间：2018-04-19 16:36

本文选题：复方柳叶消毒剂 + 不同时空　；参考：《中国消毒学杂志》2017年08期

【摘要】：目的探究复方柳叶熏蒸消毒剂对居室和养殖场空间的消毒效果及安全性。方法参照我国《消毒技术规范》空气消毒检测方法分别进行实验室试验、现场试验及动物毒性试验。结果复方柳叶熏蒸消毒剂对1 m~3实验室试验中的白色葡萄球菌杀菌率为99.99%;不同季节试验中对35 m~3公寓现场自然菌消亡率均大于90%;对35m~3养殖场自然菌消亡率均大于90%。安全性评价试验显示:小鼠急性经口毒性LD_(50)值大于5 000 mg/m~3,小鼠急性吸入毒性LC_(50)值在2 h内大于10 000 mg/m~3,对家兔皮肤无刺激,对兔眼有轻微刺激性。结论复方柳叶熏蒸消毒剂毒性低,对空气中微生物杀灭效果较好,可适用于多种空间消毒。
[Abstract]:Objective to study the disinfection effect and safety of compound willow leaf fumigation disinfectant on living room and farm space.Methods the laboratory test, field test and animal toxicity test were carried out according to the air disinfection test method.Results the bactericidal rate of compound willow leaf fumigation disinfectant to staphylococcus albicans in 1 mm3 laboratory test was 99.99%; in different season test, the natural bacteria extinction rate of 35mm3 apartment was higher than 90%; the death rate of natural bacteria in 35m~3 farm was more than 900.Results the bactericidal rate of compound willow leaf fumigation disinfectant was 99.99% in laboratory test.The safety evaluation test showed that the acute oral LDI _ (50) value of mice was greater than 5 000 mg / m ~ (3), and the acute inhalation toxicity of mice was greater than 10 000 mg / m ~ (-1) in 2 h, which had no irritation to rabbit skin and slight irritation to rabbit's eyes.Conclusion compound willow leaf fumigation disinfectant has low toxicity and is effective in killing microorganism in air. It can be used in many kinds of space disinfection.
【作者单位】：广东药科大学中药学院;广东固生堂中医养生健康科技股份有限公司;
【基金】：广东省科技厅项目(2016A020226018) 中山市科技局协同创新项目(2016C1021)
【分类号】：R187.2

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