应用Kaplan-Meier法评估首剂含麻疹成份疫苗接种率

发布时间：2018-04-21 16:36

本文选题：Kaplan-Meier法 + 含麻疹成份疫苗　；参考：《中国卫生统计》2017年02期

【摘要】：目的应用Kaplan-Meier法评估宁波市鄞州区适龄儿童含麻疹成份疫苗(measles-containing vaccine,MCV)初次免疫(MCV_1)的接种情况。方法通过宁波市免疫规划信息管理系统收集2012-2014年出生儿童的MCV_1免疫史资料,采用Kaplan-Meier方法评价MCV_1接种情况。结果宁波市鄞州区2012-2014年出生儿童59182人,MCV_1接种率为99.86%,及时接种率为92.49%;MCV_18月龄时点累计接种率为92.83%(95%CI:92.72%~92.93%),12月龄时点累计接种率为99.10%(95%CI:99.06%~99.14%),MCV_1时点累计接种率在8~10月龄时呈现较快增长,之后增长速率缓慢;经对数秩检验,本地户籍儿童MCV_1及时接种率高于外地户籍儿童,差异有统计学意义(χ~2=537.789,P0.001),日接种服务接种门诊管辖的儿童MCV_1及时接种率高于周接种服务接种门诊的儿童,差异有统计学意义(χ~2=12.930,P0.001)。结论宁波市鄞州区儿童MCV_1接种及时性较好,但仍需关注提前接种问题,儿童户籍类型和接种门诊服务频次影响MCV_1及时接种率;Kaplan-Meier法是一种快速评估MCV_1及时接种率的有效方法,值得在接种门诊疫苗接种率监测中推广。
[Abstract]:Objective to evaluate the vaccination of measles vaccine in children of Yinzhou district, Ningbo by Kaplan-Meier method. Methods the data of MCV_1 immunization history of children born from 2012 to 2014 were collected by Ningbo Immunization Planning Information Management system. Kaplan-Meier method was used to evaluate the vaccination status of MCV_1. Results the inoculation rate of 59182 children born in Yinzhou District of Ningbo from 2012 to 2014 was 99.86 and the cumulative coverage rate of MCV1 was 92.499.49. The cumulative coverage rate of MCV1 was 92.8395% CI92.933% at 12 months old. The cumulative coverage rate of MCV1 was increased rapidly at 810 months old. After that, the growth rate was slow, and the MCV_1 coverage rate of local registered children was higher than that of non-resident children by logarithmic rank test. There was a significant difference (蠂 ~ 2 ~ 2 ~ (2) 537. 789) (P ~ (0.001)). The rate of MCV_1 timely vaccination in daily inoculation service was higher than that in weekly inoculation service (蠂 ~ (2) 2 ~ (12.930)) (P ~ (0.001)). Conclusion the timeliness of MCV_1 vaccination for children in Yinzhou District of Ningbo City is good, but attention should be paid to the problem of early vaccination. Kaplan-Meier method is an effective method to evaluate the timely vaccination rate of MCV_1 by using Kaplan-Meier method, which is influenced by the type of household registration of children and the frequency of vaccination outpatient service. It is worth popularizing in vaccination rate monitoring.
【作者单位】：宁波市鄞州区邱隘中心卫生院;宁波市鄞州区疾病预防控制中心;浙江中医药大学流行病学与卫生统计学教研室;
【基金】：宁波市鄞州区科技局第三批科技计划项目[鄞科(2015)96号]
【分类号】：R186

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