中西医结合治疗煤工尘肺合并慢性阻塞性肺疾病的效果

发布时间：2018-05-02 14:00

本文选题：中西医结合 + 煤工尘肺　；参考：《广东医学》2017年06期

【摘要】：目的探讨中西医结合治疗煤工尘肺合并慢性阻塞性肺疾病(COPD)的临床疗效。方法选取煤工尘肺合并COPD患者110例,采用随机数字表法分为两组,对照组55例实施西医疗法,观察组55例实施中西医结合疗法,于治疗前后行肺功能检测和生活质量评定,比较两组临床病症改善情况和不良反应情况。结果治疗后,两组肺功能指标[第1秒用力呼气量(FEV1)、用力肺活量(FVC)、最大通气量(MVV)、一氧化碳弥散总量(DLCO)、千克摄氧量(VO_2/kg)、氧脉搏(VO_2/HR)、动脉血二氧化碳分压(PaCO_2)、呼气峰流速(PEF)]增加(P0.05)。两组肺功能指标[残气量(RV)、功能残气量(FRC)、潮气量(TV)、呼吸频率(BR)]生活质量评分(症状、活动受限、疾病影响、总分)降低(P0.05)。观察组肺功能指标(FEV1、FVC、MVV、DLCO、VO_2/kg、VO_2/HR、PaCO_2、PEF)、临床病症(咳嗽、咳痰、气喘、肺部湿Up音)改善率高于对照组(P0.05)。观察组肺功能指标(RV、FRC、TV、BR)、生活质量评分(症状、活动受限、疾病影响、总分)低于对照组(P0.05)。两组不良反应比较,差异无统计学意义(P0.05)。结论中西医结合治疗煤工尘肺合并慢阻肺是安全有效的,可显著改善患者肺功能指标和临床表征,并提高其生活质量。
[Abstract]:Objective to investigate the clinical effect of combined traditional Chinese and western medicine on coal worker pneumoconiosis with chronic obstructive pulmonary disease (COPD). Methods 110 coal worker pneumoconiosis patients with COPD were randomly divided into two groups: the control group (55 cases) were treated with western medicine, the observation group (55 cases) were treated with the combination of traditional Chinese and western medicine, the lung function and quality of life were evaluated before and after treatment. The improvement of clinical symptoms and adverse reactions were compared between the two groups. Results after treatment, the pulmonary function indexes [forced expiratory volume (FEV1), forced vital capacity (FVCU), maximal ventilation volume (MVV), total diffusion of carbon monoxide (CO), total carbon monoxide dispersion (DLCOC), kg oxygen uptake (VO), VO _ 2 / HRR, PaCo2U, PEF) increased in both groups after the treatment (1 second forced expiratory volume (FEV1), forced vital capacity (FV), maximum ventilation volume (MVV), total diffusion of carbon monoxide (CO), VO _ 2 / HRR, Paco _ (2), peak expiratory flow rate (PEF). The quality of life score (symptom, activity limitation, disease effect, total score) of lung function index (RVV, FRCU, TVV, BRR) was decreased in both groups (P 0.05). In the observation group, the improvement rate of the pulmonary function index (FEV1 / FVC+ MVV / DLCOV / DLCOV / 2 / kg / kg vs / kg / kg / kg / kg / kg / kg / kg / kg The lung function index of the observation group was lower than that of the control group (P 0.05), and the quality of life score (symptom, activity limitation, disease effect, total score) was lower than that in the control group (P < 0.05). There was no significant difference in adverse reactions between the two groups (P 0.05). Conclusion it is safe and effective to treat coal worker pneumoconiosis with chronic obstructive pulmonary disease by integrated traditional Chinese and western medicine, which can improve the pulmonary function index and clinical manifestation, and improve the quality of life of the patients.
【作者单位】：华北理工大学公共卫生学院;华北理工大学生命科学学院;华北理工大学附属医院呼吸内科;华北理工大学附属医院麻醉科;
【分类号】：R563.9;R135.2

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