同位素稀释的气相色谱-质谱法测定食品模拟物中邻苯二甲酸酯类增塑剂

发布时间：2018-05-11 02:11

  本文选题：同位素稀释法 + 食品模拟物　； 参考：《卫生研究》2015年01期

【摘要】：目的建立同位素稀释法测定4种食品模拟物中18种邻苯二甲酸酯(PAEs)类增塑剂的方法。方法水模拟物、3%(W/V)乙酸模拟物和20%乙醇模拟物中的18种增塑剂用正己烷萃取,95%乙醇模拟物加水稀释至20%乙醇后,再用正己烷萃取,采用GC-MS进行分析,同位素稀释法定性定量。结果 18种PAEs经内标校正后的线性R2≥0.9991;线性范围DINP和DIDP为0.2~5.0 mg/L,DMEP、DEEP和DBEP为0.02~2.0 mg/L,其他13种化合物的线性范围为0.005~2.0 mg/L;18种PAEs的内标相对回收率85.3%~115.0%,DIDP和DINP的定量限为200.0μg/L,其余16种PAEs的定量限为0.1~6.7μg/L,RSD≤10%。结论与以往的国标方法相比,该方法扩大了邻苯二甲酸酯类的检测范围,解决了高醇模拟物的检测结果不稳定的问题,采用同位素稀释法定性定量,结果更准确,方法更简单、可靠。
[Abstract]:Objective to establish an isotopic dilution method for the determination of 18 phthalates (PAEs) plasticizers in four food simulants. Methods Eighteen plasticizers of water analogue W / V) acetic acid and 20% ethanol were extracted with n-hexane, then diluted to 20% ethanol with water, then extracted with n-hexane, analyzed by GC-MS, and determined qualitatively by isotope dilution method. Results the linear range of 18 PAEs was 0.9991, the linear range of DINP and DIDP was 0.2mg / L DMEPU DEEP and DBEP was 0.02 mg / L, the linear range of the other 13 compounds was 0.0052.0 mg / L 18 PAEs, the relative recoveries of 18 PAEs were 85.3mgL / L, the quantification limit of DIDP and DINP was 200.0 渭 g / L, the other 16 kinds of compounds had a linear range of 200.0 渭 g 路L ~ (-1). The quantitative limit of PAEs was 0.1 渭 g / L 鈮，

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