辽宁、河南和湖南省591名成年居民血清Ghrelin水平与体成分及脂代谢相关细胞因子关系的分析

发布时间：2018-05-12 11:43

本文选题：成人 + Ghrelin　；参考：《卫生研究》2015年06期

【摘要】：目的了解成年居民血清Ghrelin水平与体成分及脂代谢相关细胞因子的关系。方法选取辽宁、河南和湖南三省591名60岁以下城乡成年居民作为研究对象,测量身高、体重、腰围、臀围、体脂百分比,计算体质指数、腰臀比,测定血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、Ghrelin、瘦素、血清钙及载脂蛋白A1/载脂蛋白B。结果成年男性居民Ghrelin浓度为24.12μg/L,女性为23.62μg/L,差异无统计学意义。随血清Ghrelin水平的升高,腰围、体质指数、腰臀比、超重/肥胖率、中心性肥胖率、体脂百分比、总胆固醇、甘油三酯、低密度脂蛋白胆固醇及血清瘦素水平逐渐降低(P0.05),血清高密度脂蛋白胆固醇及载脂蛋白A1/载脂蛋白B呈现逐渐增高的趋势(P0.05),臀围和血清钙水平变化趋势不明显。相关分析结果显示,Ghrelin浓度与BMI、腰围、腰臀比、体脂百分比、总胆固醇、低密度脂蛋白胆固醇以及瘦素明显相关(P0.05)。结论 Ghrelin水平与体成分及脂代谢相关细胞因子有关联,但与瘦素和体脂百分比的相关更为密切。
[Abstract]:Objective to understand the relationship between serum Ghrelin level, body composition and lipid metabolism related cytokines in adult residents. Methods 591 adult residents under 60 years of age in Liaoning, Henan and Hunan were selected as subjects, and the height, weight, waist circumference, hip circumference, body fat percentage were measured, body mass index, waist hip ratio, serum total cholesterol, glycerol, and glycerol were measured. Three ester, low density lipoprotein cholesterol, high density lipoprotein cholesterol, Ghrelin, leptin, serum calcium and apolipoprotein A1/ apolipoprotein B., the Ghrelin concentration of adult male residents was 24.12 mu g/L, and the female was 23.62 mu g/L, the difference was not statistically significant. With the increase of serum Ghrelin level, the waist circumference, body mass index, waist hip ratio, overweight / obesity rate, The rate of heart obesity, body fat percentage, total cholesterol, triglyceride, low density lipoprotein cholesterol and serum leptin level gradually decreased (P0.05). The serum high density lipoprotein cholesterol and apolipoprotein A1/ apolipoprotein B showed an increasing trend (P0.05), the trend of hip and serum calcium levels was not obvious. Correlation analysis showed that Ghr Elin concentration was significantly associated with BMI, waist circumference, waist to hip ratio, body fat percentage, total cholesterol, low density lipoprotein cholesterol and leptin (P0.05). Conclusion Ghrelin levels are associated with body components and lipid metabolism related cytokines, but are more closely related to leptin and body fat percentages.

【作者单位】：中国疾病预防控制中心营养与健康所;
【基金】：国家自然科学基金(No.81172666) 中国疾病预防控制中心青年基金(No.2013B103)
【分类号】：R151

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