斑马鱼对化合物影响学习认知与记忆的探索分析
发布时间:2018-05-24 03:19
本文选题:斑马鱼 + 认知 ; 参考:《毒理学杂志》2017年03期
【摘要】:正1前言随着科学技术的发展,新化学物质日益增多。目前部分化合物的毒性已被阐明,而大部分化学物质对健康的潜在影响尚未完全清楚,所以对外源化合物的危险度评价显得尤为重要与紧迫。传统毒理学实验常用啮齿类动物作为实验对象,但是其花费大,实验周期长,难以对大量物质进行高通量试验。随着3R(reduction,replacement and refinement)原则的实施,整
[Abstract]:With the development of science and technology, new chemical substances are increasing day by day. At present, the toxicity of some compounds has been clarified, but the potential health effects of most chemicals have not been fully understood, so the risk assessment of exogenous compounds is particularly important and urgent. Rodents are often used as experimental objects in traditional toxicological experiments, but they are expensive and have a long experimental period, so it is difficult to carry out high-throughput experiments on a large number of substances. With the implementation of the 3R / R reduction / replacement and definition principle,
【作者单位】: 汕头大学医学院公共卫生与预防医学教研室;
【基金】:广东省自然科学基金(2014A030313474)
【分类号】:R114
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