荞麦粉对高脂膳食大鼠体内抗氧化活性的影响

发布时间：2018-06-18 01:38

本文选题：荞麦粉 + 高脂膳食　；参考：《食品工业科技》2015年14期

【摘要】：研究了荞麦粉(buckwheat,BW)对高脂膳食大鼠体内抗氧化活性的影响。将50只成年Wistar雄性大鼠随机分为基础对照组、高脂模型对照组、荞麦粉低、中、高剂量组(1、5、10g/kg·d),喂养30d后,测定血清中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)的活性及丙二醛(MDA)的含量和肝脏组织中超氧化物歧化酶(SOD)活性及丙二醛(MDA)的含量;并观察主动脉结构。结果显示,荞麦粉中、高剂量组与模型对照组相比,荞麦粉可使高脂膳食大鼠血清SOD、GSH-PX的活性增强(p0.05)及MDA的含量显著减少(p0.05);可使肝脏中SOD活性显著增强(p0.05),但MDA的含量显著减少(p0.05);主动脉光镜结构显示荞麦粉对高脂膳食大鼠肝脏具有保护作用。说明荞麦粉具有调节高脂膳食大鼠抗氧化的能力。
[Abstract]:The effect of buckwheat (BW) on antioxidant activity in high fat diet rats was studied. Fifty adult male Wistar rats were randomly divided into basic control group, hyperlipidemia model control group, buckwheat powder low, middle and high dose groups, and fed with 10 g / kg dai for 30 days. The activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), the content of malondialdehyde (MDA), the activity of superoxide dismutase (SOD) and malondialdehyde (MDA) in liver tissue and the content of malondialdehyde (MDA) in serum were determined. The results showed that, in buckwheat flour, the high dose group was compared with the model control group. Buckwheat powder could increase the activity of SOD- GSH-PX in serum and decrease the content of MDA in serum of rats with high fat diet, increase the activity of SOD in liver, but decrease the content of MDA significantly. The structure of aorta light microscope showed that buckwheat powder had effect on high-fat diet. The rat liver has protective effect. The results showed that buckwheat powder had the ability to regulate the antioxidant ability of high fat diet rats.
【作者单位】：吉林医药学院公共卫生学院;吉林省中医药管理局二级实验室;吉林医药学院实验中心机能实验室;
【基金】：吉林省科技发展计划基金(201105089)
【分类号】：R151

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