中国3~12岁儿童自报食物过敏与食物不耐受的相关因素分析

发布时间：2018-06-22 19:00

本文选题：儿童 + 食物过敏　；参考：《卫生研究》2015年02期

【摘要】：目的了解中国3~12岁儿童食物过敏和食物不耐受的流行情况,探讨其相关因素。方法采用多阶段整群抽样方法,选取七城市(北京、苏州、广州、郑州、成都、兰州和沈阳)和两农村(河北省邢台市南和县和邢台县),共抽取1792名3~12岁儿童进行问卷调查,并用Logistic回归分析儿童自报食物过敏与食物不耐受的相关因素。结果儿童自报食物过敏率为8.4%,食物不耐受率为7.7%。最常见的引起儿童食物过敏的食物为海鲜、鱼、鸡蛋、水果和牛奶。多因素分析结果显示父母有过敏史为儿童食物过敏的危险因素[OR=4.49(95%CI 2.52~8.01),P0.01],挑食为儿童食物不耐受的危险因素[OR=2.40(95%CI 1.43~4.02),P0.01],母亲文化程度高为儿童食物不耐受的保护因素(母亲文化程度为大学及以上者相对于初中及以下者[OR=0.40(95%CI 0.20~0.80),P=0.01]。结论儿童食物过敏和食物不耐受的发生与遗传因素和父母文化程度与家庭经济状况等环境因素密切相关。
[Abstract]:Objective to investigate the prevalence of food allergy and food intolerance in 3-year-old children in China. Methods A total of 1792 children aged 12 years old were selected from seven cities (Beijing, Suzhou, Guangzhou, Zhengzhou, Chengdu, Lanzhou and Shenyang) and two rural areas (Nanhe County and Xingtai County, Xingtai City, Hebei Province) by multi-stage cluster sampling. Logistic regression analysis was used to analyze the correlation factors between food allergy and food intolerance in children. Results the rate of food allergy and food intolerance were 8.4 and 7.7 respectively. The most common foods that cause food allergies in children are seafood, fish, eggs, fruits and milk. Multivariate analysis showed that parents had a history of allergy as a risk factor for food allergy in children [OR4.49 (95 CI 2.52 / 8.01) P 0.01], selective feeding was a risk factor for children's food intolerance [OR2.40 (95CI 1.434.02) P 0.01], and mother's high educational level was a protective factor for children's food intolerance (mother's text). The degree of transformation was higher than that of junior high school [ORX 0.40 (95 CI 0.20 / 0.80) P0. 01]. Conclusion the occurrence of food allergy and food intolerance in children is closely related to the environmental factors such as genetic factors, parents' education level and family economic status.
【作者单位】：北京大学公共卫生学院;中粮营养健康研究院;
【分类号】：R153.2

【参考文献】