湖北省黄石市1985—2014年3819例肺癌发病特征分析

发布时间：2018-07-27 18:34

【摘要】：目的分析近30年内黄石市中心医院肿瘤内科新发肺癌患者在性别、年龄、吸烟、病理类型、城乡分布等发病特征的变化,为肺癌防治提供临床资料。方法收集3 819例新发肺癌患者临床资料,每10年为一时间段,比较3个10年间肺癌发病特征的变化。结果 3个10年间女性肺癌所占比例明显增加(χ~2=20.724,P0.01)。肺癌患者平均年龄在60岁左右。吸烟者人数比例在3个10年间均大于60%,差异有统计学意义(χ~2=0.333,P=0.847)。鳞癌所占比例在3个10年间分别是49.65%、46.46%、40.15%,差别有统计学意义(χ~2=20.511,P0.01)。腺癌所占比例分别是35.5%、39.41%、46.78%,差别有统计学意义(χ~2=170.494,P0.01)。初诊合并有恶性胸水患者明显增加(χ~2=52.191,P0.01)。农村患者所占比例明显升高(χ~2=30.507,P0.01)。结论吸烟作为一个独立因素,一直影响黄石市近30年来肺癌发病。女性肺癌患者、肺腺癌患者、农村肺癌患者所占比例明显增加,初诊合并恶性胸水患者增加,这些特点为本地区肺癌防治计划提供重要依据。
[Abstract]:Objective to analyze the changes in sex, age, smoking, pathological type, urban and rural distribution of newly diagnosed lung cancer patients in Department of Oncology, Huangshi Central Hospital in recent 30 years, and to provide clinical data for the prevention and treatment of lung cancer. Methods the clinical data of 3 819 patients with newly diagnosed lung cancer were collected and compared every 10 years. Results the proportion of female lung cancer increased significantly in the past 10 years (蠂 2 + 20.724 P 0.01). The average age of lung cancer patients was about 60 years old. The proportion of smokers was higher than 60 in 3 10 years, the difference was statistically significant (蠂 2 / 0.333P < 0. 847). The proportion of squamous cell carcinoma in three 10 years was 49.65 and 46.46, respectively. The difference was statistically significant (蠂 ~ 2 + 20.511 / P0.01). The proportion of adenocarcinoma was 39.41 and 46.78, respectively. The difference was statistically significant (蠂 ~ 2 / 170.494 / P0.01). The number of newly diagnosed patients with malignant pleural effusion increased significantly (蠂 2 = 52.191 / P 0.01). The proportion of patients in rural areas increased significantly (蠂 ~ (2 +) 30.507, P 0.01). Conclusion as an independent factor, smoking has always affected the incidence of lung cancer in Huangshi City in recent 30 years. The proportion of female lung cancer patients, lung adenocarcinoma patients and rural lung cancer patients increased significantly, and the number of newly diagnosed patients with malignant pleural effusion increased. These characteristics provide an important basis for the prevention and treatment plan of lung cancer in this area.
【作者单位】：鄂东医疗集团黄石市中心医院胸部肿瘤内科;
【基金】：湖北省卫生计生委科研基金(WJ2015MB278)
【分类号】：R181.3;R734.2

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