甘肃省藏区人群棘球蚴病流行现状调查及分析

发布时间：2018-07-28 07:13

【摘要】：目的了解甘肃省10个藏区县人群棘球蚴病流行情况。方法 2011年9月-2012年6月在甘肃省10个藏族自治州(县)进行分层随机抽样,每县共抽取16个行政村。采用B超扫描的方法,开展人群棘球蚴病流行情况调查。应用SPSS 20.0软件对调查结果进行描述和统计学分析,患病检出率比较采用χ~2检验。结果共抽样检查37 815人,所有调查点均发现棘球蚴病例;以县为单位的人群患病检出率为0.05%~1.59%,平均0.59%(224/37 815);患病检出率大于1%的县分别为夏河县1.59%(64/4 019)、玛曲县1.37%(44/3 206)、肃南县1.20%(60/5 000)。总人群男性患病检出率为0.53%(108/20 276)、女性患病检出率为0.66%(116/17 539),两者间差异无统计学意义(χ~2=2.647,P0.05),但藏族女性(0.71%,93/13 146)和男性(0.46%,73/15 709)患病检出率间差异有统计学意义(χ~2=7.372,P0.05)。不同年龄组间患病检出率差异有统计学意义(χ~2=109.346,P0.05),其中20~岁组最低,为0.28%(19/6 687),80~岁组最高,为2.41%(4/166),患病检出率曲线随年龄增长呈现增高趋势。不同民族间患病检出率差异无统计学意义(χ~2=1.710,P0.05),回族患病检出率最高,为0.92%(5/546)。不同职业人群间患病检出率差异有统计学意义(χ~2=33.345,P0.05),其中商人患病检出率最高,为3.32%(2/62)。共发现细粒棘球蚴病223例,多房棘球蚴病1例,无混合感染病例。其中单脏器寄生占98.21%(220/224);累及肝脏占94.76%(217/229);单包囊占81.70%(183/224);60岁及以上年龄组中多包囊比例(28.57%,22/77)高于60岁以下组(12.93%,19/147),两者间差异有统计学意义(χ~2=8.273,P0.05)。结论甘肃省10个藏区县存在不同程度的细粒棘球蚴病流行,其中夏河县、玛曲县、肃南县流行严重。藏族女性、60岁以上者、商人是该病的重点干预人群。
[Abstract]:Objective to investigate the prevalence of echinococcosis in 10 Tibetan counties in Gansu province. Methods from September 2011 to June 2012, 10 Tibetan autonomous prefectures (counties) in Gansu Province were sampled by stratified random sampling. 16 administrative villages were sampled from each county. An investigation of the prevalence of echinococcosis was carried out by B-scan. The survey results were described and statistically analyzed by SPSS 20.0 software. 蠂 2 test was used to compare the prevalence of the disease. Results A total of 37,815 people were sampled, and the incidence of echinococcosis was found in all the investigation points. The detection rate of echinococcosis was 0.05% (0.59%) in the population in county, and 1.59% (64 / 4,019) in Xiahe county (64 / 4,019), 1.37% (44 / 3 206) in Sunan county, and 1.20% (605,000%) in Sunan county, respectively, in the county of Xiahe county (64 / 4,019), Maqu county (1.37%) and Sunan county (605,000%). The prevalence rate of male was 0.53% (108 / 20 276) and that of female was 0.66% (116 / 17 539). There was no significant difference between the two groups (蠂 ~ (2) 2.647), but there was significant difference between Tibetan women (0.71% / 13 146) and male (0.46% / 15 709). There was significant difference in the prevalence rate among different age groups (蠂 2 / 109.346P 0.05), among which the 20 ~ year old group was the lowest, 0.28% (19 / 6 687) was the highest (2.41%) (4 / 166). The prevalence rate curve showed an increasing trend with the increase of age. There was no significant difference in the prevalence rate among different nationalities (蠂 2 + 1.710%, P0.05), and the highest prevalence rate was 0.92% (5 / 546) in Hui nationality. There were significant differences in the prevalence rate among different occupational groups (蠂 ~ 2 ~ (2) ~ (33) 345), in which the prevalence rate of merchants was the highest (3.32%) (2 / 62). 223 cases of echinococcosis and 1 case of multilocularis echinococcosis were found. There were 98.21% (220 / 224) of single organ parasitism, 94.76% (21.7 / 229) of liver involvement and 81.70% (183 / 224) of single cyst in the age group of 60 years or older (28.57% 22 / 77) higher than those under 60 (12.933 / 19147). The difference between the two groups was statistically significant (蠂 ~ (2 / 28) 8.273). Conclusion Echinococcus granulosus is prevalent in 10 Tibetan counties in Gansu Province, including Xiahe County, Maqu County and Sunan County. Tibetan women over 60 years old, businessmen are the focus of intervention population.
【作者单位】：甘肃省疾病预防控制中心;中国疾病预防控制中心寄生虫病预防控制所世界卫生组织热带病合作中心科技部国家级热带病国际联合研究中心卫生部寄生虫病原与媒介生物学重点实验室;
【基金】：甘肃省科技支撑计划(No.1304FKCA120) 卫生部寄生虫病原与媒介生物学重点实验室开放课题(No.WSBKTKT201305) 国家自然科学基金(No.81201315) 国家传染病重大专项(No.2009ZX10004-302)~~
【分类号】：R181.3;R532.32

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