广西沿海产盐区人群碘营养状况及甲状腺功能调查

发布时间：2018-08-20 12:43

【摘要】：目的了解广西沿海产盐区人群碘营养状况及其甲状腺功能水平,为防治碘缺乏病提供科学依据。方法选择沿海产盐区北海市铁山港区作为调查点,随机抽取637名成人进行问卷调查和甲状腺超声检查,采集尿样、血样,分别测定尿碘和血清甲状腺激素。结果人群尿碘的中位数为62.05μg/L,100μg/L的比例高达75.20%。甲状腺肿大率为3.77%、甲状腺结节检出率为22.95%。甲状腺功能各项检测指标中位数分别为:甲状腺过氧化物酶抗体0.05 IU/m L,抗甲状腺球蛋白抗体0.12 IU/m L,游离碘甲状腺原氨酸4.14 pmol/L,游离甲状腺素15.07 pmol/L,促甲状腺激素1.45μIU/m L;甲状腺功能异常率为8.48%,其中,低游离甲状腺素血症2.35%、亚甲减2.20%、甲减1.10%、亚甲亢1.73%、甲亢1.10%;甲状腺自身免疫性抗体阳性率为24.80%,其中,甲状腺过氧化物酶抗体阳性率为19.15%、抗甲状腺球蛋白抗体阳性率为17.58%。结论当地人群碘营养状况欠佳,应加强常规碘营养和甲状腺功能监测,科学补碘持续消除碘缺乏病。
[Abstract]:Objective to investigate the iodine nutritional status and thyroid function of the population in salt producing areas along the coast of Guangxi, and to provide scientific basis for the prevention and treatment of iodine deficiency disorders. Methods A total of 637 adults were randomly selected from Tieshangang District of Beihai City, the coastal salt producing area, for questionnaire investigation and thyroid ultrasound examination. Urine samples and blood samples were collected, and urine iodine and serum thyroid hormones were determined respectively. Results the median of urinary iodine was 62.05 渭 g / L and 100 渭 g / L was 75.20 渭 g / L. The rate of goiter was 3.77 and the positive rate of thyroid nodule was 22.95. The median of thyroid function were: thyroid peroxidase antibody 0. 05 IU/m / L, anti thyroglobulin antibody 0. 12 IU/m / L, free iodothyronine 4. 14 mmol / L, free thyroxine 15. 07 pmol / L, thyrotropin 1. 45 渭 IU/m / L; The abnormal rate of thyroid function was 8.48, of which, Hypothyroidism 2.35, hypothyroidism 2.20, hypothyroidism 1.1010, hyperthyroidism 1.73, hyperthyroidism 1.10.The positive rate of thyroid autoimmune antibody was 24.80. The positive rate of thyroid peroxidase antibody and anti-thyroglobulin antibody were 19.15 and 17.58 respectively. Conclusion the iodine nutrition status of the local population is poor, the routine iodine nutrition and thyroid function monitoring should be strengthened, and iodine deficiency disorders should be eliminated continuously by scientific iodine supplement.
【作者单位】：广西壮族自治区疾病预防控制中心环境卫生与地方病防制所;北海市疾病预防控制中心流行病科;
【基金】：广西壮族自治区卫生厅立项课题(Z2014632)
【分类号】：R151.42

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