成年女性参考人体素辐射剂量模型的研究
发布时间：2018-10-17 20:07
【摘要】：本论文在原始女性体素剂量学模型VPCF的基础上，开发了一个基于中国（亚洲）参考人数据的体素辐射剂量模型CRAW(Chinese ReferenceAdult Woman)，并利用蒙特卡罗FLUKA程序模拟计算得到了光子、质子以及π介子在AP及PA两种标准照射几何下的剂量转换系数。 在个体女性体素模型VPCF的基础上，依据中国参考人数据以及ICRP70号报告中骨组织分布数据，通过对骨骼进行二次分割以及对器官进行调整等过程，开发建立起能代表中国成年女性的参考人体素辐射剂量模型CRAW。该模型依据ICRP骨组织数据计算得到了19个骨骼部位的骨组织的含量，根据这些骨组织数对骨骼进行了二次分割，建立起了用中国男性参考人体素模型（CRAM）同原始成年女性体素模型VPCF相结合的骨模型RBM-site-specific，考虑了红骨髓、黄骨髓、骨小梁等骨组织的分布。采用Matlab软件“膨胀”和“腐蚀”与Photoshp手动分割相结合的方法对器官体积进行了调整，使器官质量与中国参考人数据相一致。最终建立了一个身高158cm，体重54kg，，体素尺寸为1.774mm×1.774mm×4.85mm，包含37个人体主要器官组织的成年女性参考人体素模型。 利用CRAW模型在蒙特卡罗FLUKA程序中进行计算，得到了一套能代表中国成年女性参考人的光子（0.02MeV-10MeV）、质子(0.02GeV-10TeV)、π介子（0.001GeV-10TeV）在AP以及PA标准照射情况下的外照射剂量转换系数。为皮肤、红骨髓、骨表面等分布较为特殊的辐射敏感器官选择了较合适的剂量计算方法。 对不同照射几何、器官的大小、位置、形状以及个体差异对剂量的影响进行了深入分析和讨论。结果表明这些因素对低能入射粒子在AP方向与其它模型的剂量偏差影响较大，而对于中能以及高能粒子其则影响很小。
[Abstract]:Based on the primordial female voxel dosimetry model (VPCF), a voxel radiation dose model (CRAW (Chinese ReferenceAdult Woman),) based on Chinese (Asian) reference human data was developed in this paper. The photons were calculated by Monte Carlo FLUKA program. Dose conversion coefficients of protons and 蟺 mesons under two standard irradiation geometry of AP and PA. On the basis of individual female voxel model VPCF, according to Chinese reference human data and bone tissue distribution data in ICRP70 report, the bone was divided twice and organs were adjusted. Development of a reference dose model CRAW. for Chinese adult women Based on the ICRP bone tissue data, the bone tissue content of 19 bone sites was calculated, and the bone was further partitioned according to the number of bone tissues. The bone model RBM-site-specific, which combines the Chinese male reference human body hormone model (CRAM) with the primitive adult female voxel model VPCF, takes into account the distribution of bone tissues such as red bone marrow, yellow bone marrow and trabeculae. The method of Matlab software "expansion" and "corrosion" combined with manual division of Photoshp is used to adjust organ volume to make organ quality consistent with Chinese reference human data. Finally, an adult female reference body hormone model with height of 158 cm, body weight of 54 kg and volume size of 1.774mm 脳 1.774mm 脳 4.85 mm was established, which included 37 major organs and tissues of human body. By using the CRAW model in Monte Carlo FLUKA program, a set of external dose conversion coefficients for 0.02MeV-10MeV, 0.02GeV-10TeV and 0.001GeV-10TeV in AP and PA standard irradiation are obtained. A more suitable dose calculation method was chosen for radiation sensitive organs with special distribution on skin, red bone marrow and bone surface. The effects of different irradiation geometry, organ size, position, shape and individual difference on dose were analyzed and discussed. The results show that these factors have a great effect on the dose deviation between the low energy incident particles and other models in the AP direction, but have little effect on the medium energy and high energy particles.
【学位授予单位】：哈尔滨工程大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R144.1
本文编号：2277816
[Abstract]:Based on the primordial female voxel dosimetry model (VPCF), a voxel radiation dose model (CRAW (Chinese ReferenceAdult Woman),) based on Chinese (Asian) reference human data was developed in this paper. The photons were calculated by Monte Carlo FLUKA program. Dose conversion coefficients of protons and 蟺 mesons under two standard irradiation geometry of AP and PA. On the basis of individual female voxel model VPCF, according to Chinese reference human data and bone tissue distribution data in ICRP70 report, the bone was divided twice and organs were adjusted. Development of a reference dose model CRAW. for Chinese adult women Based on the ICRP bone tissue data, the bone tissue content of 19 bone sites was calculated, and the bone was further partitioned according to the number of bone tissues. The bone model RBM-site-specific, which combines the Chinese male reference human body hormone model (CRAM) with the primitive adult female voxel model VPCF, takes into account the distribution of bone tissues such as red bone marrow, yellow bone marrow and trabeculae. The method of Matlab software "expansion" and "corrosion" combined with manual division of Photoshp is used to adjust organ volume to make organ quality consistent with Chinese reference human data. Finally, an adult female reference body hormone model with height of 158 cm, body weight of 54 kg and volume size of 1.774mm 脳 1.774mm 脳 4.85 mm was established, which included 37 major organs and tissues of human body. By using the CRAW model in Monte Carlo FLUKA program, a set of external dose conversion coefficients for 0.02MeV-10MeV, 0.02GeV-10TeV and 0.001GeV-10TeV in AP and PA standard irradiation are obtained. A more suitable dose calculation method was chosen for radiation sensitive organs with special distribution on skin, red bone marrow and bone surface. The effects of different irradiation geometry, organ size, position, shape and individual difference on dose were analyzed and discussed. The results show that these factors have a great effect on the dose deviation between the low energy incident particles and other models in the AP direction, but have little effect on the medium energy and high energy particles.
【学位授予单位】：哈尔滨工程大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R144.1
【参考文献】
相关期刊论文 前4条
1 张绍祥,刘正津,谭立文,邱明国,李七渝,李恺,崔高宇,郭燕丽,刘光久,单锦露,刘继军,张伟国,陈金华,王健,陈伟,陆明,游箭,庞学利,肖红,许忠信,王欲u&,邓俊辉,唐泽圣;首例中国女性数字化可视人体数据集完成[J];第三军医大学学报;2003年04期
2 张斌全;马吉增;程建平;杨端节;刘立业;;使用人体躯干物理模型的CT模型和蒙特卡罗方法校准肺部计数器[J];辐射防护;2006年02期
3 曾志;李君利;贾向红;许峰;黄增信;;空间辐射剂量及屏蔽效应研究[J];清华大学学报(自然科学版);2008年03期
4 徐谢,赵自强,石成玉,张田田;基于美国可视人项目图像的成年男子解剖模型及其在医学虚拟仿真上的应用[J];中国基础科学;2002年06期
本文编号：2277816
本文链接：https://www.wllwen.com/yixuelunwen/yufangyixuelunwen/2277816.html
