妇科千金胶囊和去氧孕烯炔雌醇片用于人流术后恢复的临床观察

发布时间：2018-12-14 18:37

【摘要】：人工流产术(artificial abortion operation)是避孕失败的补救方法,是指妊娠14周以内,因意外妊娠、优生或疾病等原因而采用手术终止妊娠的方法,它包括手术流产与药物流产,手术流产又分为负压吸引术(vacuum aspiration)和钳刮术(dilation clamp and curettage)。本篇论文所讨论的为手术流产中的负压吸引术。目的：为减少人工流产术后可能发生的并发症以及降低重复流产率,改善人流术后妇女的生殖健康。本论文对人工流产术后立即服用复方口服避孕药——去氧孕烯炔雌醇片(妈富隆Marvelon)和(或)妇科千金胶囊的妇女进行临床观察,分析其作用机理同时观察其临床疗效。方法：选取2010年6月～2010年9月来武汉市妇女儿童医疗保健中心计划生育专科门诊,要求进行人工流产手术的妇女400例。将之按照前来门诊就诊的先后顺序随机分为治疗组和对照组,每组各有200例患者。两组患者在年龄、孕次、孕囊大小等一般资料经统计学处理后无显著性差异(P0.05),具有可比性。治疗组的200例患者自手术当日开始,使用妇科千金胶囊2片,口服,每日3次,共8天,并且于每晚睡前口服去氧孕烯炔雌醇片1片,共21天；对照组的200例患者于手术当日开始,于每晚睡前口服去氧孕烯炔雌醇片1片,共21天。两组患者于术后常规口服甲硝唑片和诺氟沙星胶囊以预防感染,并详细填写月经卡,记录阴道流血时间和流血量,并且两组的患者均在流产术后的第8天、第15天和第一次月经来潮之后来我院门诊随诊以观察药物的临床疗效。结果：据观察显示,两组病例的妇女在治疗之后治疗组伴随症状较对照组均有明显改善。 (1)妇科千金胶囊和去氧孕烯炔雌醇片组的阴道流血时间少于去氧孕烯炔雌醇片组,具有统计学意义(P0.05)。 (2)妇科千金胶囊和去氧孕烯炔雌醇片组的阴道流血量少于去氧孕烯炔雌醇片组,具有统计学意义(P0.05)。 (3)妇科千金胶囊和去氧孕烯炔雌醇片组术后月经恢复时间短于对照组,具有统计学意义(P0.05)。结论：因此,人工流产术后及时服用妇科千金胶囊和去氧孕烯炔雌醇片可缩短阴道流血时间、减少流血量,并减少人工流产术后并发症的发生,又能有效的避孕,降低重复人工流产的发生率,还有助于月经周期的建立,可明显改善妇女的生殖健康。妇科千金胶囊服用方便,患者易接受,在用药的过程中,未发现不良反应,使之与去氧孕烯炔雌醇片合用相辅相成,取得良好临床效果,因此于人工流产术后服用妇科千金胶囊与去氧孕烯炔雌醇片的疗效肯定。
[Abstract]:Artificial abortion (artificial abortion operation) is a remedy for contraceptive failure. It refers to the method of termination of pregnancy due to accidental pregnancy, eugenics or illness within 14 weeks of pregnancy. It includes surgical abortion and drug abortion. Operative abortion is divided into negative pressure suction (vacuum aspiration) and forceps (dilation clamp and curettage). In this paper, negative pressure suction in surgical abortion is discussed. Objective: to reduce the possible complications after artificial abortion and to reduce the rate of repeated abortion and improve the reproductive health of women after abortion. In this paper, the clinical observation was carried out on women who took compound oral contraceptive-deoxypregnenyl estradiol (Marvelon) and / or gynecological Qianjin capsule immediately after induced abortion, and analyzed its mechanism of action and observed its clinical curative effect at the same time. Methods: 400 women with artificial abortion were selected from June 2010 to September 2010. The patients were randomly divided into treatment group and control group according to the order of outpatient visits. Each group had 200 patients. Two groups of patients in age, pregnancy, gestational sac size and other general data after statistical treatment, there was no significant difference (P0.05), comparable. 200 patients in the treatment group were treated with gynecological Qianjin capsule 2 tablets 3 times a day for 8 days and 1 estradiol before bedtime every night for 21 days. 200 patients in the control group were treated with deoxypregnenes estradiol tablets before bedtime for 21 days. Patients in both groups were given metronidazole tablets and norfloxacin capsules to prevent infection. Menstrual cards were filled in detail to record vaginal bleeding time and amount of bleeding. The patients in both groups were treated on the 8th day after abortion. On the 15th day and after the first menstruation, we came to our outpatient clinic to observe the clinical effect of the drug. Results: it was observed that the associated symptoms in the treatment group were significantly better than those in the control group after treatment. (1) the vaginal bleeding time of gynecological Qianjin capsule and deoxypregnenes estradiol group was less than that of deoxypregnenes estradiol group (P0.05). (2) the vaginal bleeding of gynecological Qianjin capsule and deoxypregnenes estradiol group was less than that of deoxypregnenes estradiol group (P0.05). (3) the menstrual recovery time of gynecological Qianjin capsule and deoxypregnenes estradiol group was shorter than that of control group (P0.05). Conclusion: taking gynecological Qianjin capsule and deoxypregnenes estradiol tablets in time after artificial abortion can shorten the time of vaginal bleeding, reduce the amount of bleeding, reduce the incidence of complications after artificial abortion, and can be effective contraception. Reducing the incidence of repeated abortion can also contribute to the establishment of menstrual cycle and significantly improve women's reproductive health. Gynecological Qianjin capsule is convenient to take and easy for patients to accept. No adverse reactions were found in the course of medication, which made it complementary to deoxypregnenes estradiol tablets and achieved good clinical effect. Therefore, the curative effect of gynecological Qianjin capsule and deoxypregnenes estradiol tablets after artificial abortion was confirmed.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R169.42

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