职业紧张对油田野外作业工人神经递质水平的影响

发布时间：2019-03-19 14:59

【摘要】：目的探讨油田野外作业工人职业紧张对神经递质水平的影响。方法采用职业紧张问卷(OSI-R)对工龄≥1年的178名油田野外作业工人进行问卷调查,并测定其血清中去甲肾上腺素(NE)、5羟色胺(5-HT)、神经肽Y(NPY)和P物质(SP)水平。结果工龄≤15年组的油田野外作业工人血清5羟色胺、NE和P物质水平低于工龄15年组,差异具有统计学意义(P0.05);不同职业紧张程度组之间5羟色胺、NE、神经肽Y和P物质水平的比较差异均有统计学意义(P0.05),两两比较发现,高度职业紧张组大于低度职业紧张组;偏相关分析发现油田野外作业工人职业紧张与5羟色胺、NE、P物质呈正相关关系(P0.05);与神经肽Y呈负相关关系(P0.05)。结论油田野外作业工人职业紧张与血清神经肽类、单胺类神经递质有相关性,职业紧张可以影响血清神经肽类、单胺类神经递质水平。
[Abstract]:Objective to investigate the effect of occupational stress on neurotransmitter level in field workers. Methods the occupational stress questionnaire (OSI-R) was used to investigate the serum norepinephrine (NE),) 5-hydroxytryptamine (5-HT) of 178 field workers who had been working for more than 1 year, and the serum concentrations of noradrenaline 5-hydroxytryptamine (5-HT) were measured. Neuropeptide Y (NPY) and substance P (SP) levels. Results the serum levels of serotonin, NE and substance P were significantly lower in the field workers than those in the 15-year-old group (P0.05). The levels of serotonin, NE, neuropeptide Y and substance P in different occupational stress groups were significantly different (P0.05). It was found that the level of high occupational stress group was higher than that of low occupational stress group. Partial correlation analysis showed that occupational stress was positively correlated with serotonin and NE,P (P0.05) and negatively with neuropeptide Y (P0.05). Conclusion there is a correlation between occupational stress and serum neuropeptide and monoamine neurotransmitters. Occupational stress can affect the levels of serum neuropeptides and monoamine neurotransmitters.
【作者单位】：新疆医科大学公共卫生学院劳环教研室;南通大学公共卫生学院;
【基金】：国家自然科学基金(No.81260424,81260425)
【分类号】：R131

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