ECT胃排空测定技术对功能性消化不良胃排空患者临床评分和血浆酰基化ghrelin水平的评价作用

发布时间：2017-12-27 17:16

本文关键词：ECT胃排空测定技术对功能性消化不良胃排空患者临床评分和血浆酰基化ghrelin水平的评价作用　出处：《世界华人消化杂志》2016年11期 　论文类型：期刊论文

【摘要】：目的:探讨应用发射型计算机断层扫描(emission computed tomography,ECT)技术对功能性消化不良胃排空的影响因素.方法:收集2012-06/2015-04延边大学附属医院收治的功能性消化不良胃排空患者的临床资料72例作为实验组A.选取经ECT核素标记检测提示胃排空延迟者72例为实验组B.选取同时期来延边大学附属医院进行健康体检的志愿者72例作为对照组.对实验组A进行SPECT胃排空检测.实验组B采取口服西沙比利治疗.观察实验组A和对照组T1/2时间、最大残留率(maximum rate of residual,EAOM)、全胃及各分区面积,观察实验组B治疗效果.结果:实验组A的T1/2在近端胃、远端胃方面,均显著长于对照组(P0.05).实验组A EAOM在近端胃、远端胃、中间横带(midgastric transverse band,MTB)区方面,均显著高于对照组(P0.05).实验组A在近端胃、远端胃、MTB区、全胃的面积方面,均显著高于对照组(P0.05).实验组B采取西沙比利治疗.72例患者近胃端T1/2从69.24 min±9.33 min下降至48.55 min±8.64min,患者残留率从42.88%下降至29.99%,治疗后效果优于治疗前,治疗前后比较,差异有统计学意义(P0.05);患者服药前MTB宽度为3.33 cm±0.09 cm,服药后MTB宽度为2.68 cm±0.09 cm,治疗后MTB宽度低于治疗前,治疗前后比较,差异有统计学意义(P0.05).结论:应用ECT技术能够检测功能性消化不良胃排空的影响因素,患者经西沙比利治疗后,效果较好.
[Abstract]:Objective: To explore the application of emission computed tomography (emission computed tomography, ECT) influence factors on functional dyspepsia gastric emptying. Methods: from the Affiliated Hospital of Yanbian University 2012-06/2015-04 clinical data of gastric emptying in patients with functional dyspepsia in 72 cases as experimental group A. selected by ECT labeled detection indicated that the delayed gastric emptying. 72 cases of the experimental group B. select the same period to the Affiliated Hospital of Yanbian University of healthy volunteers as a control group of 72 cases were detected. SPECT on gastric emptying in experimental group. The experimental group adopted B A and Do Si Shah Billy treatment. The experimental group A and control group T1/2 time, maximum residue rate (maximum rate of, residual, EAOM) the stomach and the partition area, was observed in the experimental group B treatment. Results: the experimental group of A T1/2 in the proximal stomach and distal stomach, significantly longer than the control group (P0.05) The experimental group A EAOM in the proximal stomach and distal gastric midgastric transverse band (midgastric transverse, band, MTB) area, were significantly higher than control group (P0.05). The experimental group A in the proximal stomach and distal gastric area MTB, stomach area, were significantly higher than control group (P0.05). The experimental group B.72 patients take Si Shah Billy in the treatment of proximal gastric T1/2 decreased from 69.24 min to 48.55 min + 9.33 min + 8.64min patients with residual rate decreased from 42.88% to 29.99%, better than the treatment before, after treatment, the difference was statistically significant (P0.05); patients before taking the MTB width of 3.33 cm + 0.09 cm, after taking the MTB width of 2.68 cm + 0.09 cm, width of MTB after treatment lower than before treatment, after treatment, the difference was statistically significant (P0.05). Conclusion: the application of ECT technology can influence factors of functional dyspepsia gastric emptying of patients after cisapride treatment, the effect is Good.
【作者单位】：延边大学附属医院核医学科;
【分类号】：R57;R817.4
【正文快照】： 0 引言胃主要是靠压力的作用使得食物中液体成分得以排出, 然后固体成分逐步被消化成微粒,利于幽门排出. 这一过程和中枢神经系统、自主神经系统、胃肠激素等有关系[1]. 功能性消化不良(functional dyspepsia, FD)引起的胃排空障碍对患者的生活质量有着严重影响. 其发病机制

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