双源CT低剂量成像结合纯化单能谱技术在超重者冠状动脉成像中的研究

发布时间：2018-02-04 12:08

本文关键词： 冠状动脉成像低剂量纯化单能谱双能量成像　出处：《临床放射学杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的探讨双源CT低剂量能量成像模式下纯化单能谱技术在改善超重者冠状动脉血管图像质量中的价值。方法将120例受检者随机均等分为两组,A组采用前瞻性心电门控扫描,B组采用双能量成像模式,图像重组均采用滤波反投影法(FBP法);将B组数据按6个单能谱ke V水平(65 ke V、70 ke V、75 ke V、80 ke V、85 ke V、90 ke V)进行重组。测量各组主动脉根部(左冠状动脉开口水平)管腔内的CT值、噪声值(SD)、信噪比(SNR)、对比噪声比(CNR)。采用随机区组设计的方差分析比较不同单能谱ke V水平各指标,选择最佳ke V;比较最佳ke V水平的B组与A组间各测量指标及辐射剂量。结果 B组不同ke V水平主动脉(左冠状动脉开口处)CT值、SD、SNR、CNR的差异均有统计学意义(P0.05),75 ke V水平有较高的CT值且SNR及CNR值最高,同时降低了SD,故选择75 ke V为最佳单能谱图像;75 ke V水平B组的CT值、SNR及CNR显著高于A组,SD显著低于A组,差异有统计学意义(P0.05)。A组图像主观评分为(4.63±0.25)分,B组为(4.79±0.06)分,差异有统计学意义(P0.05)。B组有效辐射剂量(ED)为(3.3±0.4)m Sv,A组为(6.8±0.7)m Sv,两组间差异有统计学意义(P0.05)。结论在双能量低剂量成像条件下,最佳单能量谱ke V水平为75 ke V时能够提高超重者的图像质量。
[Abstract]:Objective to investigate the value of purified single energy spectrum (SPE) technique in improving the image quality of coronary artery in overweight patients under dual-source CT low-dose energy imaging. Methods 120 subjects were randomly divided into two groups. Group A used prospective ECG gated scan group B using dual-energy imaging mode, the image was reconstructed by filtering back projection method and FBP method. The data of group B were measured at the level of 65 ke V ~ 70 ke V ~ (70) ke V ~ (75) ke V ~ (80) ke V ~ (85) ke V according to 6 single energy spectra. The CT value, noise value and SNR of aortic root (level of left coronary artery opening) were measured. The variance analysis of random block design was used to compare each index of different single energy spectrum keV level, and the best ke V was selected. Results the values of SDS-SNR were measured at different levels of aorta (left coronary artery opening) between group B and group A. The difference of CNR was statistically significant. There was a higher CT value and the highest SNR and CNR value in 75 Kev of P0.05, and the SD was decreased at the same time. Therefore, 75keV was chosen as the best single energy spectrum image. The CT value of 75 Kev level in group B was significantly higher than that in group A and SD was significantly lower than that in group A. The difference was statistically significant. The subjective score of image in group A was 4.63 卤0.25) and that in group B was 4.79 卤0.06. The effective radiation dose (EDV) of group B was 3.3 卤0.4mSvA, and that of group A was 6.8 卤0.7mSv. Conclusion under the condition of dual-energy low-dose imaging, the image quality of overweight patients can be improved when the best single energy spectrum keV level is 75keV.
【作者单位】：新疆医科大学第一附属医院影像中心;
【基金】：新疆维吾尔自治区自然科学基金面上项目(编号:2013211A083)
【分类号】：R541.4;R816.2
【正文快照】： 随着“后64层CT时代”的到来,冠状动脉CT造影(coronary CT angiography,CCTA)已成为冠心病诊断的一项重要无创性检查手段。以往CCTA检查中主要采用固定管电压的方法,获取的是混合能量下的X线冠状动脉图像,成像时其衰减的差异性,易造成图像噪声和组织间对比度的不均匀。双能量

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