个性化肝癌患者肝脏相关动脉血管的三维容积重建及其应用

发布时间：2018-02-15 22:02

本文关键词： 三维容积重建肝动脉血管肝癌 CT 个性化　出处：《北京生物医学工程》2016年06期 　论文类型：期刊论文

【摘要】：目的对个性化肝癌患者肝脏周围的动脉血管进行三维容积重建,并探讨其潜在的临床及科研应用。方法针对个性化肝癌患者,通过GE Lightspeed 64排螺旋CT进行扫描,基于300层腹部连续断层图像,利用Minics进行三维图像的容积重建,获取肝脏周围动脉血管的三维结构,结合临床探讨其在疾病诊疗和科研方面的指导作用。结果利用三维容积重建得到了局部腹腔干、肝动脉、肝固有动脉、胃左动脉等血管的三维容积模型。其中,腹腔干血管直径在12.7~18.6 mm之间,肝动脉血管直径约为5.3 mm、肝固有动脉血管直径约为4.5 mm、胃左动脉血管直径约为4.6 mm。结论利用三维容积重建技术所得的肝脏周围血管模型提供了较二维图像更直观的解剖显示和较好的后处理优势,是个性化有限元模型的基础,为肝动脉血流的有限元分析提供了数学模型,对制定更合理的肝脏外科手术方案及术后评价具有一定的指导意义。
[Abstract]:Objective to study the potential clinical and scientific application of three-dimensional volume reconstruction of arterial vessels around liver in patients with personalized liver cancer. Methods GE Lightspeed 64 slice spiral CT was used to scan the patients with personalized liver cancer. Based on 300-layer continuous tomography images of abdomen, the volume reconstruction of three-dimensional images was carried out by using Minics, and the three-dimensional structure of the vessels around the liver was obtained. Results 3D volume models of local celiac trunk, hepatic artery, proper hepatic artery and left gastric artery were obtained by three-dimensional volume reconstruction. The diameter of celiac trunk vessels was between 12.7 and 18.6 mm. The diameter of hepatic artery is about 5.3 mm, the diameter of hepatic propria artery is about 4.5 mm, and the diameter of left gastric artery is about 4.6 mm. Conclusion the model of perihepatic vessels obtained by three-dimensional volumetric reconstruction is more intuitive than that of two-dimensional images. Anatomical display and better post-processing advantages, It is the basis of personalized finite element model and provides a mathematical model for the finite element analysis of hepatic artery blood flow. It has a certain guiding significance for the formulation of more reasonable liver surgery plan and postoperative evaluation.
【作者单位】：首都医科大学附属北京佑安医院放射科;北京工业大学生命科学与生物工程学院;
【分类号】：R735.7;R730.44

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