颅脑CTP对Willis环后循环变异脑血流灌注的评价

发布时间：2018-03-07 18:42

本文选题：CTA　切入点：颅脑CTP　出处：《安徽医科大学学报》2015年12期 　论文类型：期刊论文

【摘要】：利用头颈CT血管成像(CTA)技术筛查出单侧颅底动脉环后循环变异患者,分为变异优势侧组和劣势侧组,再根据前循环是否有变异分为前循环完整组和非完整组,后运用颅脑CT灌注(CTP)技术分别测量两组双侧大脑后动脉供血区域脑组织血容量(CBV)、脑组织血流量(CBF)、平均通过时间(MTT)、造影剂达峰时间(TTD)数据,运用统计学方法对优势侧和劣势侧进行配对t检验。90例颅底动脉环后循环变异的患者中右侧后交通动脉发育不良或缺失30例,右侧大脑后动脉发育不良或缺失5例,左侧大脑后交通动脉纤细或缺失49例,左侧大脑后动脉缺失6例。前循环完整组73例;前循环非完整组17例,其中7例为前交通动脉缺失,10例为单侧大脑前动脉A1段发育不良。前循环完整组后循环优势侧CBV、CBF、MTT、TTD与劣势侧各组经配对t检验,差异无统计学意义;前循环非完整组后循环优势侧CBV、TTD与劣势侧经配对t检验,差异无统计学意义,MTT、TTD两组间比较差异有统计学意义(P0.05)。在前循环完整组,颅底动脉环后循环变异劣势侧与优势侧脑血流灌注无明显差异;在前循环非完整组,颅底动脉环后循环变异劣势侧MTT大于优势侧,CBF小于优势侧,与临床不明原因的晕厥可能有相关作用。
[Abstract]:The patients with posterior circulation variation of unilateral basilar artery ring were screened by CT angiography (CTAA) technique. The patients were divided into two groups: the dominant group and the inferior group. According to the variation of the anterior circulation, the patients were divided into two groups: the intact anterior circulation group and the non-complete anterior circulation group. After that, the CBV volume, CBFV, MTT and TTDwere measured by CT perfusion technique in the bilateral posterior cerebral artery region of the brain in two groups, and the mean transit time (MTT) and the peak time of contrast medium (TTD) were measured. T test was performed on the dominant side and inferior side by means of statistical method. Among 90 patients, 30 had hypoplasia or absence of right posterior communicating artery, 5 had hypoplasia or absence of right posterior cerebral artery. The left posterior communicating artery was slender or absent in 49 cases, left posterior cerebral artery in 6 cases, complete anterior circulation group in 73 cases and incomplete anterior circulation group in 17 cases. Among them, 7 cases were anterior communicating artery missing and 10 cases were unilateral anterior cerebral artery A1 dysplasia. There was no significant difference between CBVV CBFFT TTD and inferior side by paired t test. There was no significant difference between the two groups by paired t test. There was no significant difference between the two groups (P 0.05). In the intact anterior circulation group, there was no significant difference between the two groups. There was no significant difference between inferior side and dominant side of cerebral blood perfusion in inferior side and dominant side of posterior circulation of basilar artery ring, MTT of inferior side of variation of posterior circulation of basilar artery ring was larger than that of dominant side in incomplete group of anterior circulation. It may be related to syncope of unknown clinical cause.
【作者单位】：安徽医科大学第二附属医院放射科;上海市徐汇区大华医院放射科;
【基金】：安徽省质量工程项目-医学影像学教学团队(编号:2014jxtd119) 安徽高校省级自然科学研究项目(编号:KJ2011Z188)
【分类号】：R816.1

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