鼻咽癌调强放疗中摆位误差的变化趋势:基于千伏级锥形束CT的前瞻性研究

发布时间：2018-03-16 10:48

本文选题：鼻咽癌　切入点：锥形束CT　出处：《放射学实践》2017年08期 　论文类型：期刊论文

【摘要】：目的:基于千伏级锥形束CT(kV-CBCT)分析鼻咽癌调强放射治疗(IMRT)中分次间摆位误差的变化趋势,提高放疗准确性。方法:64例鼻咽癌患者进行调强治疗,治疗过程中共进行9次kV-CBCT扫描来确定患者的位置,根据前三次摆位误差的规律来指导后续治疗中患者体位的摆放。分别将第1~3、4~6和7~9次kV-CBCT扫描中患者的位置信息设为A、B和C组。比较三组的摆位及靶区边界误差的差异。结果:A组在X(左-右)、Y(头-脚)和Z(前-后)轴方向上的平移和旋转误差分别为(0.58±1.49)、(0.82±1.96)、(0.53±1.64)mm和0.60°±0.50°、0.82°±0.58°、0.62°±0.53°,B组分别为(0.28±1.08)、(0.44±1.35)、(0.11±1.15)mm和0.68°±0.70°、0.80°±0.52°、0.63°±0.49°,C组分别为(0.32±1.23)、(0.42±1.51)、(0.25±1.24)mm和0.61°±0.53°、0.62°±0.53°、0.60°±0.50°。A、B、C三组在X、Y、Z轴上计划靶区的外放边界(MPTV)分别为2.49、3.42、2.47mm,1.46、2.05、1.08mm和1.66、2.11、1.49mm。A组与B、C两组在X、Y、Z轴上的平移误差的差异有统计学意义(P0.05),而B、C两组间的误差差异无统计学意义(P0.05)。结论:在鼻咽癌调强放射治疗中,基于kV-CBCT扫描分析摆位误差的规律,能较好地降低后续治疗中的摆位误差。
[Abstract]:Objective: to improve the accuracy of radiotherapy for nasopharyngeal carcinoma (NPC) by analyzing the variation trend of interposition error in intensity modulated radiotherapy (IMRTT) based on CTKV-CBCT.Methods: 64 patients with nasopharyngeal carcinoma were treated with intensity modulation therapy. A total of nine kV-CBCT scans were performed during the course of the treatment to determine the location of the patient. According to the rule of the first three pendulum errors, the postural position of the patients in the follow-up treatment was guided. The position information of the patients in the first three times of kV-CBCT scanning was set as group A B and group C. the difference between the positioning and the boundary error of the target area was compared among the three groups. Results the errors of translation and rotation in the X (left to right) and Z (anterior to posterior) axes in group A were 0.58 卤1.49 掳0.82 卤1.96 掳0.53 卤1.64 mm and 0.60 掳卤0.50 掳0.82 掳卤0.58 掳0.62 掳卤0.58 掳0.62 掳卤0.53 掳B and 0.28 卤1.35 掳0.44 卤1.15 mm and 0.68 掳卤0.70 掳0.80 掳卤0.52 掳0.63 掳卤0.49 掳C, respectively, and 0.32 卤1.23 卤0.42 卤1.51mm and 0.61 掳卤0.53 掳0.62 掳0.62 掳0.53 掳0.53 掳0.53 掳0.53 卤0.53 掳and 0.68 掳卤0.80 掳卤0.52 掳0.63 掳卤0.49 掳C respectively. There were significant differences in the translation errors between group A and group B C on the Xanya Z axis (2.49 卤3.42mm / 2.47mm) and 1.662.111.49mm.A respectively, but there was no significant difference between the two groups (P 0.05). Conclusion: in intensive radiotherapy for nasopharyngeal carcinoma, there is no significant difference in the error between the two groups (P0.05. conclusion: in intensive radiation therapy for nasopharyngeal carcinoma, there is no significant difference in translation error between the two groups. Based on kV-CBCT scan, the law of pendulum error can be well reduced in subsequent treatment.
【作者单位】：武汉同济医院肿瘤放疗中心;
【分类号】：R730.44;R739.63

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