冠状动脉CT造影对诊断冠脉不同类型斑块所致管腔狭窄的准确性研究

发布时间：2018-03-16 13:11

本文选题：冠状动脉　切入点：粥样斑块　出处：《中国医学计算机成像杂志》2015年04期 　论文类型：期刊论文

【摘要】：目的:评价冠状动脉CT造影(CCTA)诊断不同类型的冠状动脉粥样斑块所致冠状动脉狭窄的价值与限度。方法:连续80例完成CCTA及侵入性冠状动脉造影(ICA)检查的疑诊冠状动脉狭窄患者(男性62例,女性18例,年龄30~77岁,平均58岁)纳入研究,冠状动脉粥样斑块类型分为钙化性、非钙化性和混合性。以冠状动脉节段为单位,以ICA结果为金标准,运用相关分析及;Bland-Altman分析评价2种检查技术诊断三种斑块所致冠状动脉狭窄的一致性。结果:最终诊断明显冠脉狭窄(狭窄程度≥50%)49例108个节段;两种技术诊断钙化斑块性冠状动脉明显狭窄一致性差(r=0.720,P0.01),非钙化和混合斑块性明显狭窄一致性良好(r=0.895,r=0.900,P0.01)。结论:CCTA诊断非钙化性和混合性斑块所致冠状动脉狭窄准确性较好,钙化斑块性狭窄的诊断需慎重。
[Abstract]:Objective: To evaluate the coronary artery CT angiography (CCTA) diagnostic value and limitation of different types of coronary artery plaque induced by coronary artery stenosis. Methods: 80 consecutive patients with complete CCTA and invasive coronary angiography (ICA) examination of the suspected patients with coronary artery stenosis (male 62 cases, female 18 cases, age 30~77 years old, average at the age of 58) included in the study of coronary atherosclerotic plaque types into calcified and non calcified and mixed with coronary artery segments as a unit, with ICA as a golden standard, using correlation analysis and Bland-Altman analysis; evaluation of 2 techniques in diagnosis of consistency of three kinds of plaque induced by coronary artery stenosis. Results: the final diagnosis of significant coronary stenosis (more than 50% stenosis) in 49 cases of 108 segments; two techniques in the diagnosis of calcified plaque of coronary artery stenosis and poor consistency (r=0.720, P0.01), non calcified and mixed plaque stenosis good consistency Good (r=0.895, r=0.900, P0.01). Conclusion: CCTA is more accurate in diagnosing coronary artery stenosis caused by non calcified and mixed plaques, and the diagnosis of calcified plaque stenosis should be cautious.

【作者单位】：新疆医科大学第一附属医院影像中心;
【基金】：新疆维吾尔自治区自然科学基金No.2013211A083 新疆乌鲁木齐市科学技术计划项目No.Y121320019 新疆医科大学一附院自然基金No.2013ZRZD12~~
【分类号】：R541.4;R816.2

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