CT灌注扫描对尤瑞克林治疗急性期脑梗死老年患者的效果

发布时间：2018-03-21 01:27

本文选题：CT灌注扫描　切入点：尤瑞克林　出处：《中国老年学杂志》2015年01期 　论文类型：期刊论文

【摘要】：目的探讨CT灌注扫描技术(CTPI)对尤瑞克林治疗老年急性期脑梗死的临床效果。方法 2012年1月至2014年1月选取168例经头部CT或磁共振成像(MRI)确诊为急性期脑梗死的老年患者,随机分为常规治疗组及尤瑞克林组各84例,常规治疗组口服阿司匹林,同时给予奥扎格雷钠静脉滴注治疗,尤瑞克林组在常规治疗基础上静脉滴注尤瑞克林,分别于治疗前后对两组患者行CTPI,观察两组患者治疗前后中心区及半暗带区脑灌注成像相对比值。对比两组患者治疗效果及治疗前后脑梗死面积及神经功能缺损评分(NIHSS)改善情况。结果尤瑞克林组总有效率(92.86%)高于常规治疗组(76.19%)(P0.05)。两组患者治疗后中心区及半暗带区中脑血容量(CBV)、脑血流量(CBF)、达峰时间(TTP)均高于治疗前(P0.05),且尤瑞克林组治疗后中心区及半暗带区中CBV、CBF、TTP均高于常规治疗组(P0.05)。尤瑞克林组治疗后梗死面积及NIHSS评分显著少于常规治疗组。结论通过CT灌注扫描可观察尤瑞克林对老年急性期脑梗死患者病灶中心区及半暗带区血流灌注的改善情况,对评价脑梗死患者预后具有重要的意义。
[Abstract]:Objective to investigate the clinical effect of CT perfusion scanning technique (CTPI) in the treatment of acute cerebral infarction in elderly patients. Methods from January 2012 to January 2014, 168 elderly patients diagnosed as acute cerebral infarction by CT or Mr imaging were selected. They were randomly divided into routine treatment group (n = 84) and eurekline group (n = 84). Aspirin was given orally in routine treatment group and sodium ozagrel was given intravenously. CTPI was performed before and after treatment to observe the relative ratio of cerebral perfusion imaging in the central and penumbra regions before and after treatment in the two groups. The effect of treatment and the assessment of cerebral infarct size and neurological deficit before and after treatment were compared between the two groups. Results the total effective rate of Eurekline group (92.86) was higher than that of routine treatment group (76.19%) (P 0.05). After treatment, CBVV, CBFV, CBFV, TTPwere higher in the central and penumbra regions of the two groups than in the pre-treatment (P 0.05). After treatment, the TTP of CBV and CBF in the central and penumbra regions of the group was higher than that in the routine treatment group (P 0.05). The infarct size and NIHSS score in the eucrine group after treatment were significantly lower than those in the routine treatment group. Conclusion the CT perfusion scan can be used to observe the effect of eurethrin on the elderly acute. The improvement of blood perfusion in the central and penumbra regions of patients with cerebral infarction, It is of great significance to evaluate the prognosis of patients with cerebral infarction.
【作者单位】：沧州市中心医院神经内五科;
【分类号】：R743.3;R816.2

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