直肠神经内分泌肿瘤的影像学分析

发布时间：2018-03-22 09:12

本文选题：直肠神经内分泌肿瘤/影像学　切入点：病理分级　出处：《中华肿瘤防治杂志》2015年11期 　论文类型：期刊论文

【摘要】：目的分析新病理分级下直肠神经内分泌肿瘤(neuroendocrine neoplasm,NEN)的影像学表现,提高对直肠NEN的术前诊断率。方法收集2010-03-01-2014-03-31经手术病理确诊、有完整影像学资料的直肠NEN患者37例,分析直肠NEN的影像学表现及不同级别间影像学表现差异。结果 37例直肠NEN均为无功能性。参照WHO 2010年消化系统肿瘤分类和2010年中国病理学诊断共识,G1级32例,G2级1例,G3级4例,单发多见(33/37)。G1~G2级33例,长径均2.0cm(平均1.0cm,G2级1例长径为5cm),边界清楚,增强均为明显强化;其中30例为黏膜面息肉样或结节隆起型病变,31例黏膜表面光滑,1例出现淋巴结转移,均未见肝转移。G3级4例,病变长径均2.0cm(平均6.4cm),均侵犯肠管1/2周以上或呈环周性生长,侵犯浆膜外或纤维膜外,边界不清楚,黏膜表面不规则,增强扫描明显强化;其中3例出现淋巴结转移,1例出现肝转移。结论增强扫描明显强化是直肠神经内分泌肿瘤的影像特征,低级别(G1、G2级)病灶长径小,形态规则,远处转移少见,而高级别(G3级)病变长径大,侵袭性生长特点明显。
[Abstract]:Objective to analyze the imaging findings of neuroendocrine neoplasm (NEN) in rectum neuroendocrine neoplasms.Methods 37 cases of rectal NEN with complete imaging data were collected from 2010-03-01-2014-03-31, which were confirmed by operation and pathology. Results 37 cases of rectal NEN were nonfunctional. According to the classification of digestive system tumors of WHO 2010 and the consensus of pathological diagnosis in China in 2010, 32 cases of G 1 grade were diagnosed as G 2. Grade 1, grade G 3, 4 cases, 33 cases of 33 / 37 / 37 / G _ 1 / G _ 2 were found in single cases, with a mean length of 2.0 cm (mean 1.0 cm / G ~ (-2), 5 cm ~ (-1)), the margin was clear and enhancement was obvious, 30 cases were polypoid or nodular protuberant lesions of mucous membrane and 31 cases had smooth mucosal surface metastasis, and 1 case had lymph node metastasis, and 30 cases (30 cases) had mucosal polypoid or nodular protuberant lesions, and 1 case had lymph node metastasis. No liver metastases were found in 4 cases of grade G3, and the lesion had an average length of 2.0 cm (average 6.4 cm). All of them invaded the intestinal duct for more than 1 / 2 weeks or showed circumferential growth, invasion of extraserous or fibrous membrane, unclear boundaries, irregular mucosal surface, and enhanced enhanced scanning. Conclusion enhanced enhanced scanning is the imaging feature of rectal neuroendocrine tumors. The lesions of low grade G _ 1 G _ 2) are small in length, regular in shape and rare in distant metastasis. The long diameter and invasive growth of the lesion were obvious.
【作者单位】：北京协和医学院中国医学科学院肿瘤医院影像诊断科;
【基金】：中国胃肠胰神经内分泌肿瘤临床流行病学研究辉瑞公司基金(WS1910269)
【分类号】：R735.37;R730.44;R445.2

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