滋阴活血颗粒联合糖皮质激素、抗生素治疗放射性肺炎的临床观察

发布时间：2018-03-23 09:29

本文选题：滋阴活血颗粒　切入点：放射性肺炎　出处：《中国中西医结合杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的观察滋阴活血颗粒联合糖皮质激素、抗生素治疗放射性肺炎患者的临床疗效。方法将放射性肺炎患者70例按照随机数字表法分为治疗组和对照组,每组35例。两组均给予激素乖抗生素治疗,治疗组加用滋阴活血颗粒,每日1剂,连续用药4周。观察治疗前后两组患者Watters临床-影像-生理(clinical radiographic physiologic,CRP)评分、卡氏评分和美国肿瘤放射治疗协作组(Radiation Therapy Oncology Group,RTOG)急性放射性损伤分级,比较两组抗生素及激素应用时间。结果所有患者均完成了观察,无脱落和死亡病例。治疗前两组Watters-CRP评分、卡氏评分及RTOG分级比较,差异无统计学意义(P0.05);与本组治疗前比较,两组治疗后RTOG分级明显改善(P0.05);与对照组比较,治疗后治疗组Watters-CRP评分降低,卡氏评分升高,抗生素和激素使用时间减少(P0.05),治疗后RTOG分级治疗组虽优于对照组,但差异无统计学意义(P0.05)。结论滋阴活血颗粒联合激素、抗生素治疗放射性肺炎,在改善Watters-CRP评分、缩短抗生素和激素用药时间、提高患者身体机能状态方面,优于单纯应用激素和抗生素治疗。
[Abstract]:Objective to observe the clinical efficacy of Ziyin Huoxue granule combined with glucocorticoid and antibiotics in the treatment of radiation pneumonia. 35 cases in each group were treated with steroid antibiotics, while in the treatment group, one dose of Ziyin Huoxue granule was given daily for 4 weeks. The Watters scores of clinical radiographic radiographic before and after treatment were observed in the two groups. Carr's score was compared with radiation Therapy Oncology Group (RTOG) acute radiation injury grade, and the time of antibiotic and hormone application was compared between the two groups. Results all the patients completed the observation, no cases of abscission and death. Before treatment, the two groups were evaluated with Watters-CRP score. Compared with before treatment, the RTOG grade of the two groups improved significantly (P 0.05), compared with the control group, the Watters-CRP score of the treatment group decreased, and the Karnox score increased, compared with the control group, the difference was not statistically significant (P 0.05), the difference between the two groups was significant (P 0.05), and the difference between the two groups was not significant (P 0.05). The use time of antibiotics and hormones decreased P0.05A, although the RTOG grading treatment group was superior to the control group, but the difference was not statistically significant (P0.050.Conclusion Ziyin Huoxue granule combined with hormone, antibiotic treatment of radiation pneumonia, improve the Watters-CRP score. It is better to shorten the time of antibiotics and hormone use and to improve the function of patients than to only use hormones and antibiotics.
【作者单位】：山东滨州医学院附属医院肿瘤科;
【分类号】：R730.55

【共引文献】