血清相关肿瘤标志物检测联合钼靶CR摄影及高频超声成像在临床触诊阴性乳腺癌诊断中的应用

发布时间：2018-03-30 18:03

本文选题：乳腺肿瘤　切入点：乳房X线摄影技术　出处：《实用医学杂志》2015年04期

【摘要】：目的:分析钼靶CR摄影、高频超声成像和血清肿瘤标志物检测单独及联合检查在触诊阴性乳腺癌诊断中的应用价值。方法:收集经过病理明确诊断的临床触诊阴性乳腺癌65例,均完成钼靶CR摄影、高频超声成像及血清肿瘤标志物检测三种检查,分别计算三种检查方法单独及联合诊断的敏感性、特异性及准确性,分析各种不同检查方法及联合检查方法之间的差别及不同腺体类型乳腺之间钼靶CR摄影诊断结果的差异。结果:钼靶CR摄影与超声联合检查的诊断敏感性、特异性和准确性分别为91.87%、85.43%和88.71%,两者的单独检查结果分别为80.15%、87.53%、83.26%和81.18%、88.95%、84.15%,三者联合检查的诊断敏感性、特异性和准确性分别为78.26%、76.35%和89.27%。结论:钼靶CR摄影与超声联合诊断临床触诊阴性乳腺癌的准确性明显提高,血清肿瘤标志物检测对于早期乳腺癌的诊断意义低于另外两种检查方法。
[Abstract]:Objective: to analyze the value of molybdenum target CR imaging, high frequency ultrasound imaging and serum tumor marker detection in the diagnosis of palpation negative breast cancer. Methods: 65 cases of clinical palpation negative breast cancer diagnosed by pathology were collected. The sensitivity, specificity and accuracy of the three methods were calculated, including molybdenum target CR imaging, high frequency ultrasound imaging and serum tumor marker detection. The difference between different examination methods and combined examination methods and the difference of mammography diagnosis results between different glandular types of mammary glands were analyzed. Results: the diagnostic sensitivity of molybdenum target CR combined with ultrasound was analyzed. The specificity and accuracy were 91.87% and 85.43% and 88.71%, respectively. The results of single examination were 80.15% and 87.53%, 83.26% and 81.18%, respectively. The diagnostic sensitivity of the three joint examinations was 83.26% and 81.18%, respectively. The specificity and accuracy were 78.26% and 89.27%, respectively. Conclusion: the accuracy of the combination of molybdenum target CR and ultrasound in the diagnosis of clinical palpation negative breast cancer is obviously improved. The diagnostic value of serum tumor markers for early breast cancer is lower than that of the other two methods.
【作者单位】：佛山市顺德区妇幼保健院放射科;佛山市顺德区妇幼保健院妇产科;
【基金】：佛山市医学类科技攻关项目(编号:2014AB002013)
【分类号】：R737.9;R445.1;R730.44

【参考文献】