肝脏常见占位性病变边缘区的多b值DWI分析

发布时间：2018-05-07 13:02

本文选题：肝脏占位 + 血流灌注　；参考：《中国医学计算机成像杂志》2015年04期

【摘要】：目的:探讨多b值DWI在肝脏常见占位性病变鉴别诊断中的应用价值。方法:选取经临床证实肝脏占位性病变48例62个病灶行多b值的DWI扫描,分别拟合出10个b值ADC_(10b)图,3个低b值(0s/mm~2、50s/mm~2、100s/mm~2)ADClow图,3个高b值(500s/mm~2、750s/mm~2、1000s/mm~2)ADC_(high)图,并将ADC_(low)与ADC_(high)值之间的差异定义为ADC_(perf)值。在病变中央区及边缘区绘制两个相同大小的ROI(region of interest),分别计算ADC_(low)、ADC_(high)、ADC_(perf)、ADC_(3b)及ADC_(10b)值,分析肝脏良恶性占位及病变中央区及边缘区各ADC值之间的差异。结果:良恶性占位之间其中央区和边缘区在灌注(ADC_(perf))图上ADC值的差异均有统计学意义(P0.05),病变中央区及边缘区之间良恶性占位在ADC_(perf)图上ADC值的差异有统计学意义(P0.05);除了在ADC_(low)外,其余ADC_(10b),ADC_(high),ADC_(3b)图上良恶性占位之间中央区及边缘区ADC值的差异均有统计学意义(P0.05),恶性肿瘤中央区与边缘区ADC值的差异均有统计学意义(P0.05)。而良性占位中央区及边缘区ADC值差异,除了在ADC_(low)外,均无统计学意义(P0.05)。结论:多b值DWI技术可提供肝脏占位血流灌注特点的参考信息,与其他MRI成像序列相结合,能够提高肝脏占位性病变的诊断及鉴别诊断准确率。
[Abstract]:Objective: to evaluate the value of multi-b-value DWI in differential diagnosis of common occupying lesions of liver. Methods: a total of 62 lesions of 48 patients with clinically proven hepatic occupying lesions were examined with DWI with multiple b values, and 10 b-value ADCC / 10 b maps were fitted respectively, 3 low b values (250s / mm ~ 250s / mm ~ 2100s / mm / mm ~ 2DDC low map) and 3 high b ~ (b) values of 500s / s / mm ~ 2750s / mm / s ~ 2 ~ 10s / s / 2d / d ~ 2d / d were fitted, respectively, and the difference between the values of ADCP) and ADCS / T was defined as the value of ADCP / D). Two ROI(region of the same size were drawn in the central and marginal areas of the lesion, and the ADC values of the central and marginal areas of the lesion were calculated, respectively, and the differences between the ADC values of the benign and malignant liver and the central and marginal areas of the lesion were analyzed. Results: there were significant differences in ADC values between the central and marginal regions of benign and malignant lesions on the perfusion map (P 0.05). The difference of ADC between the central and marginal regions of benign and malignant lesions was statistically significant (P 0.05). The ADC values of central and marginal areas in benign and malignant areas were significantly different between benign and malignant lesions, and the ADC values in central and marginal areas of malignant tumors were significantly different from those in central and marginal areas of malignant tumors. However, there was no significant difference in ADC between the central and marginal areas of benign occupation except in ADC. Conclusion: Multi-b-value DWI technique can provide reference information for the characteristics of hepatic space-occupying blood flow perfusion and can be combined with other MRI imaging sequences to improve the accuracy of diagnosis and differential diagnosis of hepatic space-occupying lesions.
【作者单位】：新疆医科大学第一附属医院影像中心;新疆医科大学第一附属医院病理科;新疆医科大学第二附属医院影像中心;
【基金】：国家自然科学基金No.81360214~~
【分类号】：R575;R816.5

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