MSCT双低扫描在门静脉成像中的可行性研究

发布时间：2018-06-26 13:07

本文选题：计算机体层成像 + 低管电压　；参考：《山东大学》2014年博士论文

【摘要】：一、MSCT低管电压扫描对比剂剂量优化的实验研究目的：探讨与低管电压(kVp) CT扫描技术匹配的对比剂剂量。材料方法：配制不同对比剂含量的混合溶液(对比剂和生理盐水,单位ml,对比剂为碘海醇300mgI/ml),分别装入5只试管内,0号试管对比剂含量为2%,1-4号管对比剂含量依次较0号试管减少10%,20%,30%,40%,分别为1.8%、1.6%、1.4%、1.2%,再装入标准腹部体膜小孔内,分别行90kVp和120kVp腹部条件扫描,分别测量5只试管内对比剂溶液的CT值,比较不同对比剂含量溶液90kVp管电压时的CT值,以及90kVp各不同对比剂含量溶液的CT值与120kVp0试管对比剂溶液CT值的差异,进行统计学分析。结果：90kVp条件下,0-4号试管的CT值随着对比剂剂量的减少而降低,0和1号试管内对比剂溶液的CT值无统计学意义,0、1与2、3、4号试管间对比剂溶液CT值有统计学意义。90kVp条件下,0、1、2号试管内对比剂溶液的CT值均高于120kVp的0号管,90kVp条件下的3、4号管(即对比剂剂量减少30-40%)对比剂溶液CT值与120kVp的0号管对比剂溶液CT值间无统计学差异,但辐射剂量降低约33%。结论：低管电压扫描时减少30-40%的对比剂剂量,可以达到常规扫描模式的强化效果,同时辐射剂量降低33%。二、MSCT低管电压扫描门静脉成像延迟时间的选择目的：探讨MSCT90kVp门静脉成像延迟时间的选择。材料方法：46例行腹部CT强化扫描的患者,随机分为A、B两组,每组23例,均行9OkVp.395mAs腹部扫描,对比剂为碘海醇300mgI/ml,注射剂量为1.2ml/kg,速率3.0ml/s,行门脉期扫描时延迟时间分别为A组50s,B组60s,选取门脉期图像进行分析,分别测量肝实质及门静脉CT值,比较A、B两组患者肝实质CT值、门静脉CT值及不同延迟时间肝实质和门静脉CT值差值,进行统计分析。结果：A组门静脉平均CT值为197.2±27.2Hu,B组为178.3±24.0Hu,A组高于B组,二者有统计学差异；A组肝实质平均CT值为109.8±15.3Hu,B组肝实质平均CT值为108.4±12.9Hu,二者无统计学差异；A、B两组门静脉与肝实质的差值分别为87.4±23.8Hu,69.9±30.8Hu,A组高于B组,二者差异有统计学意义。结论：90kVp低管电压腹部CT扫描,门静脉成像延迟时间50s强化效果优于60s。异；ED分别为3.8±O.4mSv,5.7±0.5mSv,二者有统计学差异,90kVp组辐射剂量减少了33%。结论：MSCT双低扫描可用于正常体质量指数患者的门静脉成像,且门静脉显示优于常规扫描,同时降低了辐射剂量,减少了对比剂用量。
[Abstract]:Experimental study on dose optimization of MSCT low tube voltage scanning contrast agent objective: to study the dose of contrast agent matching with low tube voltage (KVP) CT scanning technique. Materials methods: mixed solutions with different contents of contrast agents (contrast agent and saline) were prepared. In unit ml, the contrast agent was iodiol 300mgI / ml, which was put into 5 test tubes, respectively. The contrast agent content in tube 0 was 2X 1-4. The content of contrast agent in tube No. 0 was decreased by 10% 2020% 30% and 40g / ml, respectively, which was 1.8% 1.6% 1. 2% and 1. 2% respectively, and then loaded into the small hole of the standard abdominal membrane. The CT values of contrast medium solution in 5 test tubes were measured by abdominal conditional scanning of 90 kV p and 120 kV p, respectively, and the CT values of 90 kV P tube voltage with different contrast agent contents were compared. The difference of CT value between 90 KVP and 120 kVp0 contrast solution was analyzed statistically. Results under the condition of 90 KVP, the CT value of the test tube No. 0-4 decreased with the decrease of the dose of contrast agent. There was no significant difference between the CT value of the contrast medium solution in the 0 and 1 tubes. The CT value of the contrast medium solution in the test tube No. 4 was significantly higher than that in the control tube. The CT value of the contrast medium solution in the test tube No. 4 was significantly higher than that in the control tube. The CT value of contrast agent solution in tube No. 1 and No. 2 was higher than that in tube No. 0 with 120kVp. There was no significant difference between CT value of contrast medium solution and CT value of tube No. 0 contrast agent solution with 120kVp. The CT value of contrast agent solution in tube No. 4 (30-40% reduction of contrast agent dose) was higher than that in tube No. 0 tube with 120kVp, and the CT value of contrast agent solution in tube No. 2 was higher than that in tube No. 0 with 120kVp. But the radiation dose was reduced by about 33. Conclusion: the enhancement effect of conventional scanning mode can be achieved by reducing the dose of contrast agent by 30-40% while reducing the radiation dose by 33% during low-tube voltage scanning. The selection of delayed time of MSCT low-tube voltage scanning portal vein imaging objective: to explore the choice of delayed time of MSCT 90kVp portal vein imaging. Materials: methods Forty-six patients with abdominal CT enhanced scanning were randomly divided into two groups: group A (n = 23) and group B (n = 23), all of whom underwent 9OkVp.395mAs abdominal scan. The contrast medium was 300 mg I / ml, the dose was 1.2 ml / kg, the rate was 3.0 ml / s, and the delayed time of portal phase scanning was 60 s in group A and group B, respectively. The portal phase images were selected to analyze the CT value of hepatic parenchyma and portal vein, and the CT values of hepatic parenchyma were compared between the two groups. Ct value of portal vein, hepatic parenchyma and CT value of portal vein at different delay time were statistically analyzed. Results the average CT value of portal vein in group A was 197.2 卤27.2Huao B (178.3 卤24.0Huao) was higher than that in group B (P < 0.05). There was significant difference between the two groups. The mean CT value of hepatic parenchyma in group A was 109.8 卤15.3Hu.There was no significant difference between the two groups in CT value of hepatic parenchyma. The difference between portal vein and hepatic parenchyma in group A was higher than that in group B (87.4 卤23.8Huan69.9 卤30.8HuA, respectively), and the difference between group A and group B was statistically significant. Conclusion the enhancement effect of CT scan with low voltage abdominal CT scan at 90 KVP is better than that of 60 s with delayed time 50 s in portal vein imaging. Ed was 3.8 卤0.4 mSvN 5.7 卤0.5 mSv, respectively. The radiation dose of 90kVp group was decreased by 33%. Conclusion dual low volume MSCT scan can be used for portal vein imaging in patients with normal body mass index, and portal vein display is superior to conventional scanning, and radiation dose is reduced and contrast agent dosage is reduced.
【学位授予单位】：山东大学
【学位级别】：博士
【学位授予年份】：2014
【分类号】：R816.2

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