基于CT影像重建模型的主动脉夹层流固耦合模拟

发布时间：2018-07-11 16:27

本文选题：流固耦合 + 主动脉夹层　；参考：《水动力学研究与进展A辑》2015年06期

【摘要】：主动脉夹层是血管内壁撕裂形成真假腔而形成的一种主动脉血管疾病。由于主动脉夹层假腔破裂风险高,发病凶险,致死率较高且难以抢救,故近年来关于该病的研究得到了广泛的重视。通过流固耦合模拟,研究血液与血管壁间的相互作用,为评估病变部位的破裂风险提供了一种可行的方法。该文介绍一种基于CT影像重建的主动脉夹层流固耦合模拟方法。在本文对一例Stanford B型主动脉夹层病例研究中,在血管厚度设定上采用了分区等厚度模型,并使用六面体单元对固体部分进行了网格划分。对于血管壁部分采用了线弹性本构关系。通过对计算得出的第一主应力、壁面切应力、流场等指标的分析,帮助评估主动脉夹层的破裂风险和预测破裂位置。
[Abstract]:Aortic dissection is a kind of aortic vascular disease caused by laceration of the inner wall of the blood vessel and formation of true and false lumen. Because of the high risk of false chamber rupture of aortic dissection, the dangerous disease, the high mortality rate and the difficulty of rescue, the research on this disease has been paid more and more attention in recent years. The interaction between blood and vascular wall is studied by fluid-solid coupling simulation, which provides a feasible method for evaluating the risk of rupture. This paper introduces a method of fluid-solid coupling simulation of aortic dissection based on CT image reconstruction. In a case of Stanford B type aortic dissection, a partition isoparametric model was used to determine the thickness of blood vessels, and a hexahedron element was used to mesh the solid part. The linear elastic constitutive relation is used for the vascular wall. Through the analysis of the first principal stress, wall shear stress, flow field and so on, it is helpful to evaluate the rupture risk and predict the rupture location of aortic dissection.
【作者单位】：复旦大学力学与工程科学系;复旦大学附属中山医院血管外科复旦大学血管外科研究所;
【基金】：国家自然科学基金面上项目(81371648,81470573) 上海市自然科学基金(14ZR1403300) 上海市科委基础研究重点项目(12JC1402400) 上海市教育委员会科研创新重点项目(14ZZ012) 上海市科委医学引导类课题(124119a3501)~~
【分类号】：R543.1;R816.2

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