急性型胼胝体变性的临床表现和影像学特点
发布时间：2018-08-01 17:59
【摘要】：目的探讨急性型胼胝体变性(MBD)的临床表现和影像学特点。方法对该院诊治的3例急性型MBD患者进行回顾性分析,包括临床表现、实验室检查、影像学检查(头颅CT、MRI)和随访结果。结果 3例患者均急性起病,主要表现为意识障碍、精神异常、癫痫发作、谵妄性震颤、高热等;CT与MRI可见胼胝体膝部和压部病灶,CT示病灶为低密度,MRI表现为T1WI等或低信号,T2WI高信号,液体衰减反转恢复序列高信号,弥散加权成像(DWI)高信号,ADC等或低信号;3例均伴发双侧大脑半球白质对称性病灶,1例出现脑桥臂对称性病灶,1例胼胝体膝部及体部出现类似"三明治"样改变。结论急性型MBD临床表现多样,无特异性,但具有特征性影像学表现。
[Abstract]:Objective to investigate the clinical and imaging features of acute corpus callosum degeneration (MBD). Methods three patients with acute MBD were retrospectively analyzed, including clinical manifestation, laboratory examination, imaging examination and follow-up results. Results all of the 3 patients had acute onset, mainly manifested as disturbance of consciousness, abnormal spirit, seizure, delirium tremor. High fever isochromatic CT and MRI showed that the lesions of the corpus callosum in knee and pressure showed low density MRI with high signal intensity on T1WI isointense or hypointensity T 2WI and high signal intensity on fluid attenuated inversion recovery sequence. Diffusion weighted imaging (DWI) with high signal intensity or low signal intensity in 3 cases were accompanied by bilateral cerebral hemisphere white matter symmetry lesions. One case had a symmetrical lesion of the pons arm and the other case had similar "sandwich" like changes in the genu and body of corpus callosum. Conclusion the clinical manifestations of acute MBD are diverse and non-specific, but have characteristic imaging findings.
【作者单位】： 重庆市涪陵中心医院神经内科;中南大学湘雅医院神经内科;
【分类号】：R744.5;R445.2;R816.1
本文编号：2158388
[Abstract]:Objective to investigate the clinical and imaging features of acute corpus callosum degeneration (MBD). Methods three patients with acute MBD were retrospectively analyzed, including clinical manifestation, laboratory examination, imaging examination and follow-up results. Results all of the 3 patients had acute onset, mainly manifested as disturbance of consciousness, abnormal spirit, seizure, delirium tremor. High fever isochromatic CT and MRI showed that the lesions of the corpus callosum in knee and pressure showed low density MRI with high signal intensity on T1WI isointense or hypointensity T 2WI and high signal intensity on fluid attenuated inversion recovery sequence. Diffusion weighted imaging (DWI) with high signal intensity or low signal intensity in 3 cases were accompanied by bilateral cerebral hemisphere white matter symmetry lesions. One case had a symmetrical lesion of the pons arm and the other case had similar "sandwich" like changes in the genu and body of corpus callosum. Conclusion the clinical manifestations of acute MBD are diverse and non-specific, but have characteristic imaging findings.
【作者单位】： 重庆市涪陵中心医院神经内科;中南大学湘雅医院神经内科;
【分类号】：R744.5;R445.2;R816.1
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