多层螺旋CT评估肝癌射频消融术后肿瘤灭活的临床价值

发布时间：2018-09-07 20:19

【摘要】：目的:探讨多层螺旋CT评估肝癌射频消融(RFA)术后肿瘤灭活的临床价值。方法:采用CT灌注成像(CTP)联合CT动脉成像(CTA)及CT增强扫描评价91例肝癌患者行RFA术治疗前后肿瘤的大小、密度变化及凝固性坏死区范围,比较两种评价方法诊断肿瘤复发或残余的灵敏度、特异度和准确率。结果:CTP联合CTA诊断肿瘤复发或残余的灵敏度、特异度和准确率分别为100%、95.3%和96.2%;常规增强CT分别为33.3%、88.4%和78.8%。RFA治疗后肿瘤复发或残余的诊断灵敏度、准确率CTP联合CTA高于常规增强CT,差异有统计学意义(x~2=6.912,x~2=7.121;P0.05);特异度之间两者差异无统计学意义(x~2=0.615,P0.05)。结论:CTP联合CTA可准确地判断RFA后肿瘤有无灭活及程度,且优于常规增强CT,是RFA有效与否的有效评估方法,具有较高临床价值。
[Abstract]:Objective: to evaluate the clinical value of multislice spiral CT in the evaluation of tumor inactivation after radiofrequency ablation (RFA) of liver cancer. Methods: CT perfusion imaging (CTP) combined with CT arteriography (CTA) and CT enhanced scanning were used to evaluate the tumor size, density and coagulation necrosis area in 91 patients with hepatocellular carcinoma before and after RFA treatment. The sensitivity, specificity and accuracy of the two methods for the diagnosis of tumor recurrence or residual tumor were compared. Results the sensitivity, specificity and accuracy of CTA in the diagnosis of tumor recurrence or residual tumor were 100% and 96.2%, respectively, and the diagnostic sensitivity of conventional enhanced CT was 33.3% and 88.4%, respectively, and the sensitivity of diagnosis of tumor recurrence or residual after 78.8%.RFA treatment. The accuracy of CTP combined with CTA was significantly higher than that of conventional enhanced CT, (P 0.05), but there was no significant difference in specificity between them (P 0.05). Conclusion CTA combined with CTA can accurately judge the inactivation and degree of tumor after RFA, and is superior to conventional enhanced CT, as an effective method for evaluating the effectiveness of RFA. It is of high clinical value.
【作者单位】：邯郸市传染病医院放射科;
【分类号】：R735.7;R730.44

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