明日叶对过度训练致大鼠胃肠功能紊乱影响的研究

发布时间：2018-09-10 20:58

【摘要】：研究明日叶对过度训练致大鼠胃肠功能紊乱的作用。建立雄性大鼠过度训练模型,观察过度训练组、补充明日叶组的大鼠肠道主要菌群双歧杆菌、大肠杆菌数量,肠道代谢产物脲酶、β-半乳糖苷酶活性和主要SCFA含量,以及血浆内毒素、组织匀浆SIg A含量的变化。与正常对照组比较,过度训练组双歧杆菌数量及B/E比值显著升高,大肠杆菌数量显著降低;β-半乳糖苷酶活性及主要SCFA乙酸、丁酸含量显著降低,脲酶活性显著升高;组织匀浆SIg A含量显著下降,而血浆内毒素含量显著升高。补充明日叶组各指标与对照组比较均无显著差异。结果表明,明日叶能够从肠道菌群、肠道代谢产物及肠道屏障等几个方面对肠道微生态进行综合调理,促进肠道健康。
[Abstract]:To study the effect of tomorrow leaf on gastrointestinal dysfunction induced by overtraining in rats. The overtraining model of male rats was established to observe the activities of bifidobacterium, Escherichia coli, urease, 尾 -galactosidase and main SCFA in the intestinal tract of rats in the overtraining group and the supplement group. The changes of plasma endotoxin and SIg A content in tissue homogenate. Compared with the control group, the number of Bifidobacterium and the ratio of B / E in the overtraining group increased significantly, the number of Escherichia coli decreased significantly, the activity of 尾 -galactosidase and the main SCFA acetic acid and butyric acid decreased significantly, and the activity of urease increased significantly. The content of SIg A in tissue homogenate decreased significantly, while the plasma endotoxin content increased significantly. There was no significant difference in each index between the group supplemented with tomorrow leaf and the control group. The results showed that the microecology of intestinal tract could be treated comprehensively by tomorrow's leaves from the aspects of intestinal flora, intestinal metabolites and intestinal barrier, so as to promote intestinal health.
【作者单位】：华北理工大学公共卫生学院;唐山师范学院体育系;
【基金】：河北省教育厅项目(ZD2015122) 唐山市应用基础研究计划项目(14130254B) 2014省级大学生创新创业训练计划项目(201410081087)
【分类号】：R87

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