枕颈复合体关节间隙在不同影像中的比较研究及其临床意义
发布时间：2018-10-22 07:27
【摘要】：目的通过火棉胶微视断层切片测量和评估枕寰枢结构的关节间隙,将火棉胶微视断层切片相关结构测量数值与CT、MRI的对应数值进行比较,探讨CT、MRI对枕颈部关节间隙数据测量的精确性,明确枕颈复合体测量评估的最佳方法。 方法①采用12例正常死亡的成人尸体,取其头颈部,标本要求为中立位,无颈部疾病,以枕颈复合体作为观测对象。②先将标本进行CT、MRI横断面扫描,层间距为1mm,利用Efilm软件进行矢状位和冠状位的图像重建采集影像学图像。③然后经改良火棉胶包埋法处理标本,分别修块,脱钙、冲水、酒精梯度脱水、梯度火棉胶浸胶、包埋,整合德国产浸酒L型切片机,制备枕颈复合体的横断面(4例)、冠状面(4例)和矢状面(4例)的连续切片,层厚1mm。④取相互匹配的层面,观察并测量分析三种来源图像中的相关组织间隙。标本切片用解剖镜直接观察；CT、MRI使用Efilm软件进行测量。测量精度精确到0.01cm。 结果在火棉胶组织切片、CT、MRI中精确测量枕颈复合体各关节间隙的距离。选择评估枕颈复合体中最常用关节间隙,包括寰齿间隙(ADI)、齿突侧块间隙(LADI)、寰枕间隙(AOI)、寰枢椎间隙(AAI)、基底寰椎间隙(BAI)、基底齿突间隙(BDI)的距离,得出精确数据。得出3组数据后,利用spss软件将三组数据进行比较、统计学分析。经过统计学处理,统计结果无显著性差异。 结论①火棉胶微视断层组织切片具有良好的组织固定稳定性,测量数据最接近正常人体数据,得出数据如下：ADI3.1250±0.91613mm, LLADI6.0875±1.01621mm, RLADI5.6250±1.65422mm, LAOI2.6167±0.47258mm, RAOI2.5583±0.38954mm, LAAI2.4625±0.49262mm, RAAI2.6625±0.75012mm, BDI4.2250±1.21209mm, BAI0.4750±1.42449mm。正常枕颈复合体的间隙测量数据,可以为临床和基础研究提供精确的关节间隙数据以供参考。②结果提示火棉胶组织切片、CT、MRI中枕颈复合体各关节间隙的测量数据无统计学差异,可认为CT、MRI均可作为判定枕颈复合体关节间隙的准确方法,并且可以认为CT、MRI可以准确反映骨组织的影像,可以用CT、MRI任何一种方法进行骨组织相关的在体研究。③MRI对软组织,尤其是韧带的显影是其他影像学手段所不能比拟的,结合这个有点,所以认为MRI是评估枕颈复合体的最佳选择方法。
[Abstract]:Objective to measure and evaluate the joint space of occipitocatlantoaxial structure by using the flint gel microview section, and compare the relative structure measurement value of the occipital atlantoaxial structure with the corresponding value of CT,MRI. To investigate the accuracy of CT,MRI in measuring the space between occipitocervical joints and to determine the best method for evaluating occipitocervical complex. Methods 1Twelve adult cadavers with normal death were taken from their heads and necks. The specimens required to be neutral and without neck disease. Occipitocervical complex was used as the observation object. (2) the specimens were scanned by CT,MRI cross-sectional scanning. The image reconstruction of sagittal and coronal position was carried out by Efilm software. 3. The specimens were treated with modified clove embedding method, and the specimens were repaired, decalcified, flushed, alcohol gradient dehydrated, and gradified sponge gum soaked respectively, and the results were as follows: (1) the interval between layers was 1 mm, and the images were reconstructed in sagittal and coronal position by Efilm software. The lamellar thickness 1mm.4 was used to match the cross section (4 cases), coronal plane (4 cases) and sagittal plane (4 cases) of the occipitocervical complex. To observe and measure the tissue gaps in the three source images. The specimens were observed directly by anatomic microscope and CT,MRI was measured by Efilm software. The precision of measurement is 0. 01 cm. Results the distance between the joints of occipitocervical complex was accurately measured by CT,MRI. To evaluate the distance of the most commonly used joint space in occipitocervical complex, including (ADI), lateral mass space, (LADI), occipital space, (AOI), space, (AAI), space, (BAI), basal space, (BDI) space, and obtain accurate data. After three groups of data were obtained, the three groups of data were compared by spss software, and the statistical analysis was made. There was no significant difference in the statistical results after statistical treatment. Conclusion\;\%? The measured data of the normal occipitocervical complex can provide accurate joint space data for clinical and basic research for reference. 2 the results suggest that there is no statistical difference between the measured data of the occipitocervical complex and the joint space in CT,MRI. It can be concluded that CT,MRI can be used as an accurate method to judge the space between occipitocervical complex and joint, and that CT,MRI can accurately reflect the image of bone tissue, and that CT,MRI can be used for in vivo study of bone tissue by any method of CT,MRI. Especially the development of ligaments can not be compared with other imaging methods, so MRI is the best method to evaluate occipitocervical complex.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R445.2;R816.8
[Abstract]:Objective to measure and evaluate the joint space of occipitocatlantoaxial structure by using the flint gel microview section, and compare the relative structure measurement value of the occipital atlantoaxial structure with the corresponding value of CT,MRI. To investigate the accuracy of CT,MRI in measuring the space between occipitocervical joints and to determine the best method for evaluating occipitocervical complex. Methods 1Twelve adult cadavers with normal death were taken from their heads and necks. The specimens required to be neutral and without neck disease. Occipitocervical complex was used as the observation object. (2) the specimens were scanned by CT,MRI cross-sectional scanning. The image reconstruction of sagittal and coronal position was carried out by Efilm software. 3. The specimens were treated with modified clove embedding method, and the specimens were repaired, decalcified, flushed, alcohol gradient dehydrated, and gradified sponge gum soaked respectively, and the results were as follows: (1) the interval between layers was 1 mm, and the images were reconstructed in sagittal and coronal position by Efilm software. The lamellar thickness 1mm.4 was used to match the cross section (4 cases), coronal plane (4 cases) and sagittal plane (4 cases) of the occipitocervical complex. To observe and measure the tissue gaps in the three source images. The specimens were observed directly by anatomic microscope and CT,MRI was measured by Efilm software. The precision of measurement is 0. 01 cm. Results the distance between the joints of occipitocervical complex was accurately measured by CT,MRI. To evaluate the distance of the most commonly used joint space in occipitocervical complex, including (ADI), lateral mass space, (LADI), occipital space, (AOI), space, (AAI), space, (BAI), basal space, (BDI) space, and obtain accurate data. After three groups of data were obtained, the three groups of data were compared by spss software, and the statistical analysis was made. There was no significant difference in the statistical results after statistical treatment. Conclusion\;\%? The measured data of the normal occipitocervical complex can provide accurate joint space data for clinical and basic research for reference. 2 the results suggest that there is no statistical difference between the measured data of the occipitocervical complex and the joint space in CT,MRI. It can be concluded that CT,MRI can be used as an accurate method to judge the space between occipitocervical complex and joint, and that CT,MRI can accurately reflect the image of bone tissue, and that CT,MRI can be used for in vivo study of bone tissue by any method of CT,MRI. Especially the development of ligaments can not be compared with other imaging methods, so MRI is the best method to evaluate occipitocervical complex.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R445.2;R816.8
【参考文献】
相关期刊论文 前8条
1 巩腾;杨慧;李云生;冯世庆;;脊柱胸腰段薄层断层解剖及临床意义[J];解剖与临床;2008年03期
2 张苏;陈永珍;朱e，
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