急性运动成年人血浆胃肠激素肽水平变化的Meta分析

发布时间：2018-12-12 01:37

【摘要】：背景:有研究认为急性运动可能是通过影响胃肠激素肽的合成和分泌来调节食欲影响摄食行为,但是目前此方面的相关研究样本量较小且结果迥异。目的:运用Meta分析法评估急性运动对成年人胃肠激素肽(酪酪肽)水平的影响。方法:检索Pub Med、Google Scholar、Sport Discus、Web of Knowledge及CNKI数据库检索截止时间到2014年1月。采用Rev Man5.1软件进行Meta分析,发表性偏倚和异质性检验,数据合并和敏感性分析。结果与结论:1共有11篇符合纳入标准的文献,对18项随机对照试验188名受试者进行Meta分析急性运动对健康人血浆酪酪肽水平影响,结果发现资料有同质性合并效应量标准化均数差(SMD)合并=0.25,95%CI=0.05-0.46,P=0.01,故认为急性运动组与对照组相比酪酪肽水平在统计学上有显著性差异(P0.05),且敏感性分析并未改变Meta分析的结果。2纳入3篇急性运动对健康成人血浆酪酪肽(3-36)的影响文献,5项随机对照实验,32名受试者进行Meta分析:异质性显著,故采用随机效应模型进行分析。合并标准化均值差标准化均数差(SMD)合并=1.80,95%CI=0.27-3.32,P=0.02,故急性运动上调了酪酪肽(3-36)水平。结果提示,急性运动可以增加成年人血浆胃肠激素肽水平,其水平变化可能会与运动后摄食量变化有关。
[Abstract]:Background: some studies suggest that acute exercise may regulate appetite and food intake by affecting the synthesis and secretion of gastrointestinal hormone peptides, but at present, the sample size of this study is relatively small and the results are quite different. Aim: to evaluate the effect of acute exercise on the levels of gastrointestinal hormone peptide (tyrosine) in adults by Meta assay. Methods: the deadline for retrieval of Pub Med,Google Scholar,Sport Discus,Web of Knowledge and CNKI databases was up to January 2014. Rev Man5.1 software was used for Meta analysis, publishing bias and heterogeneity test, data merging and sensitivity analysis. Results and conclusion: 1 A total of 11 articles were included in this study. Meta was used to analyze the effect of acute exercise on plasma tyrosine levels in 18 randomized controlled subjects. The results showed that the data had homogeneity combination effect, standardized mean difference, (SMD) combination = 0.25% 95% CI, 0.05-0.46% P0. 01, and 0. 05%, 0. 05%, 0. 05%, 0. 05%, 0. 05%. It was concluded that the level of tyrosine in acute exercise group was statistically different from that in control group (P0.05). The sensitivity analysis did not change the results of Meta analysis. 2 three articles on the effect of acute exercise on plasma tyrosine (3-36) in healthy adults were included. In 5 randomized controlled trials, 32 subjects were analyzed by Meta: heterogeneity was significant. So the random effect model is used to analyze. (SMD) combined with standardized mean difference (SMD) = 1.80 ~ 95CIX 0.27-3.32 P0.02, so acute exercise upregulated the level of tyrosine (3-36). The results suggest that acute exercise can increase the plasma levels of gastrointestinal hormone peptides in adults, and the changes of the levels may be related to the changes of food intake after exercise.
【作者单位】：上海体育学院运动健身科技省部共建教育部重点实验室;
【基金】：国家自然科学基金(31000522;81472148) 上海体育学院研究国(境)外生访学项目资助(stfx20140204)~~
【分类号】：R87

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