不同反复体位改变模式对人体心血管功能影响的比较研究

发布时间：2018-12-16 02:57

【摘要】：目的：对同一组受试人群实施两种不同模式的反复体位改变刺激,研究两种反复体位改变对心血管调节功能影响的差异、刺激特点和应用方向。方法：使12名受试者在旋转床上进行两种模式的反复体位改变试验,并在试验前、后5min对受试者进行5min+75°的心血管反应测试(HUT)。反复体位改变程序如下：HDT/HUT模式：0°,5min—-15°,1.5min—+50°,1min—+15°,1.5min—+50°,1min—-15°,1.5min—+50°,1min—-30°,2min—+50°,1min—-30°,2min—+50°,1min—-30°,2min—+50°,1min—-45°,3min—+50°,1min—-45°,3min—+50°,1min—-30°,2min—+50°,1min—-15°,1.5min—+50°,1min—0°,5min: SUP/HUT模式：0°,2min—+75°,1min,重复十次。以平卧位参数为对照,选取受试者在每个体位20s、60s时的心率(HR)、血压(SBP,DBP,MBP)、每搏量(SV)、心输出量(CO)、总外周阻力(TPR)等指标时行分析。结果：1)HDT/HUT模式使受试者在之后的HUT检查时心血管反应指数(CRI)显著升高；DBP、MBP、CO在HUT1min时较试验前显著下降；SUP/HUT模式的试验对CRI值、立位时的BP没有影响。2)两种模式的反复体位改变试期间,多项心血管参数变化明显,并呈现出规律性的变化。3)除前两次体位改变外,HDT/HUT模式的△BP小于SUP/HUT模式的△BP。在每个体位(第八次除外)的20s,HDT/HUT的△SV、△CO都小于SUP/HUT的△SV、△CO.4)HDT/HUT模式中,第十次-15？0s、+5020s时的SBP(p0.05).MBP低于第一次；第十次+5060s时SBP低于第一次,DBP、MBP升高(p0.05)；TPR高于第一次(p0.05)。SUP/HUT模式中,除第十次060s时的SBP低于与第一次之外(p0.05),SBP、DBP、MBP、TPR都显著高于第一次。两种模式试验SV、CO的变化趋势相似。结论：1)两种模式的反复体位改变试验对心血管调节功能造成的影响具有一定差异；2)与HDT/HUT模式的反复体位试验相比,机体能够更好地适应SUP/HUT模式的反复体位改变试验对心血管造成的影响；3)HDT/HUT模式的反复体位改变试验有可能用于预备航天员的选拔,SUP/HUT模式的反复体位改变试验有可能用于航空、航天飞行前的“热身训练”。
[Abstract]:Objective: to study the effects of repeated postural changes on cardiovascular regulation in the same group of subjects. Methods: 12 subjects were subjected to repeated posture change tests in two different modes on a rotating bed, and (HUT). Was tested by 5min 75 掳cardiovascular response test after 5min before the trial. The procedure of repeated posture change was as follows: HDT/HUT mode: 0 掳, 5min--15 掳, 1.5min-50 掳, 1min-15 掳, 1.5min-50 掳, 1min--15 掳, 1.5min-50 掳, 1min--30 掳, 2min-50 掳, 1min--30 掳, 2min-50 掳, 1min--30 掳. 2min-50 掳, 1min--45 掳, 3min-50 掳, 1min--45 掳, 3min-50 掳, 1min--30 掳, 2min-50 掳, 1min--15 掳, 1.5min-50 掳, 1min-0 掳, 5 min: SUP/HUT mode: 0 掳, 2 min-75 掳, 1 min, repeat ten times. Heart rate (HR), blood pressure (SBP,DBP,MBP) and total peripheral resistance (TPR) of (SV), cardiac output (CO),) were measured at 20 s to 60 s in each postural position. The parameters of supine position were compared. Results: 1) HDT/HUT model significantly increased the cardiovascular response index (CRI) during the later HUT examination, DBP,MBP,CO decreased significantly at HUT1min. The SUP/HUT model test had no effect on the CRI value and the BP in standing position. 2) during the repeated posture change test of the two models, many cardiovascular parameters changed obviously and showed regular changes. 3) except for the first two changes in posture, there were significant changes in cardiovascular parameters. The BP of the HDT/HUT mode is smaller than the BP. of the SUP/HUT mode The SV, CO of 20s HDT / HUT in each position (except for the eighth time) was lower than that of SUP/HUT 's (SV, CO.4) HDT/HUT model. The SBP (p0.05). MBP) at the 10th and 5020s was lower than that of the first one. At the tenth time of 5060s, SBP was lower than that of the first time, and DBP,MBP increased (p0.05). TPR was higher than that of the first (p0.05). In the SUP/HUT model, the SBP at the tenth 060s was lower than that at the first (p0.05), and the SBP,DBP,MBP,TPR was significantly higher than that at the first time (p0.05). The variation trend of SV,CO was similar between the two models. Conclusion: 1) there are some differences in the effects of repeated posture change test between the two models on cardiovascular regulatory function; 2) compared with the repeated posture test of HDT/HUT mode, the body can better adapt to the effect of repeated posture change test of SUP/HUT mode on cardiovascular system. 3) the repeated posture change test of HDT/HUT mode may be used to prepare astronauts for selection, and the repeated posture change test of SUP/HUT mode may be used for "warm-up training" before aviation and aerospace flight.
【学位授予单位】：北京体育大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：G804.2

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