自适应迭代重建技术在CTPA中降低辐射剂量且提高图像质量的研究

发布时间：2019-02-16 22:09

【摘要】：目的探讨迭代重建技术(ASIR)在CT肺动脉造影(CTPA)中降低辐射剂量且提高图像质量的可行性。方法前瞻性连续选择2012年6月至2014年6月疑似肺动脉栓塞者150例行肺动脉CTA检查。按照体质量指数的大小,平均分配为A、B、C三组。分别为A组(常规组):50例,使用常规扫描方法行CTPA检查;B组(低剂量协议组):50例,使用降低管电流结合ASIR技术行CTPA检查;C组(低剂量协议组):50例,使用降低管电压结合ASIR技术行CTPA检查。分别对三组图像的噪声、信噪比(SNR)、对比度噪声比(CNR)、辐射剂量及图像主观评分进行统计学分析。结果 A、B、C三组的有效剂量分别为(6.5±1.7)m Sv、(2.7±0.2)m Sv、(2.4±0.1)m Sv。A组与B、C组的有效剂量差异均有统计学意义(F=149.5、P0.01)。B组与C组的有效剂量差异无统计学意义(P=0.24)。A、B、C三组的背景噪声分别为9.0±0.6、9.0±0.9、9.1±0.9,差异均无统计学意义(F=0.16、P=0.85)。A、B、C三组的SNR分别为35.3±6.2、36.1±4.8、57.8±11.6,A组与B组差异无统计学意义(P=0.70),C组与A、B组比较差异均有统计学意义(P0.01,P0.01);医师1、医师2对A、B、C组的图像主观总体评分分别为4.0±0.5、4.0±0.5、4.3±0.4;3.9±0.7、3.9±0.8、4.3±0.5。A组与B组图像质量的总体评分差异均无统计学意义(P=0.19,P=0.11)。C组图像质量的总体评分均高于A、B两组,差异均有统计学意义(P0.01、P0.01)。结论(1)CTPA检查中,使用ASIR技术的低剂量协议组与常规组相比较,患者所受到的辐射剂量大幅降低,且图像噪声无明显差异;(2)低剂量协议组中,ASIR结合低管电压的方法与ASIR结合低管电流的方法相比较,在辐射剂量无明显差异的前提下,图像质量得到了大幅提高。
[Abstract]:Objective to investigate the feasibility of iterative reconstruction technique (ASIR) to reduce radiation dose and improve image quality in CT pulmonary angiography (CT) (CTPA). Methods 150 patients with suspected pulmonary embolism from June 2012 to June 2014 were prospectively selected for pulmonary CTA examination. According to the body mass index (BMI), the three groups were equally divided into three groups. Group A (conventional group): 50 cases were examined with CTPA by conventional scanning, group B (low dose protocol group): 50 cases with CTPA by using the technique of reducing tube current and ASIR. Group C (low dose protocol group): 50 cases were examined by CTPA with reduced tube voltage and ASIR technique. The noise, SNR (SNR), contrast noise ratio (CNR), radiation dose and image subjective score of three groups of images were analyzed statistically. Results the effective doses of the three groups were (6.5 卤1.7) m Sv, (, 2.7 卤0.2) m Sv, (, 2.4 卤0.1) m Sv.A, respectively. There were significant differences in the effective doses between the three groups. There was no significant difference in effective dose between P0.01). B group and C group (P0. 24). There was no significant difference in SNR between group A and group B (P 0. 70), C and group B) (P 0.01, P < 0.05), and the SNR of group A was 35.3 卤6.2n 36.1 卤4.8n 57.8 卤11.6A, and that of group B was not significantly different from that of group B (P < 0.05), and there was no significant difference between group A and group B (P 0.01). P0.01); Doctor 1, the subjective total score of the images in group A (2) was 4.0 卤0.5 (4.0 卤0.5) and 4.3 卤0.4 (P < 0.05) respectively. There was no significant difference in the overall score of image quality between group A and group B (3.9 卤0.7) and 4.3 卤0.5.A (P < 0.01). The total score of image quality in group). C was higher than that in group A (0.19) and group B (P < 0.05). The difference was statistically significant (P0.01, P0.01). Conclusion (1) in CTPA, the radiation dose of low dose protocol group using ASIR technique was significantly lower than that of routine group, and there was no significant difference in image noise. (2) in the low dose protocol group, compared with the method of ASIR and low tube current, the image quality of ASIR combined with low tube voltage is greatly improved without obvious difference in radiation dose.
【作者单位】：江苏省扬州市苏北人民医院影像科;
【分类号】：R814.2

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