双能量扫描在肾脏占位中的应用
发布时间：2019-04-27 14:07
【摘要】：第一部分第二代双源CT虚拟平扫在肾脏占位中的应用 目的： 探讨第二代双源CT虚拟平扫(VNC)在肾脏占位性病变中的临床应用价值。方法： 对52例肾脏占位性病变的患者行常规CT平扫和双能量CT增强扫描。经liverVNC获得虚拟平扫（VNC）图像，由两名医师对VNC和常规平扫的图像质量及病灶显示情况进行评价，测量双肾病变区平均CT值、SNR及辐射剂量，并进行比较。 结果： VNC图像在病灶显示方面完全满足诊断要求，与常规平扫比较差异无统计学意义(P0.05)，3例钙化灶在VNC显示较常规平扫体积缩小。所测量各部位VNC平均CT值与常规平扫差异均无统计学意义(P0.05)；利用t检验对比分析VNC与常规平扫选在肾实质、腰大肌、主动脉及肾占位的图像，虚拟平扫（VNC）SNR略低于常规平扫(P0.05)；虚拟平扫单期DLP、有效剂量ED分别为464.50±207.37mGycm、6.96±3.11mSv，均低于常规平扫的640.94±195.26mGycm、9.16±2.92mSv，差异均有统计学意义(t值分别为4.842、2.588，P值均0.05）。 结论： 对与肾脏占位性病变，第二代双源CT可提供高质量虚拟图像，，并且将明显低辐射剂量。 第二部分双源CT双能量扫描碘图在肾脏恶性占位中的应用 目的: 探讨双能CT双能量扫描碘图在肾脏恶性占位中的应用价值。 方法: 回顾性分析并经病理证实的35例肾细胞癌，测定肾脏肿瘤皮髓交界期、实质期、腹主动脉的含碘浓度及病灶与主动脉含碘浓度比值。比较透明细胞癌和非透明细胞癌两组病灶碘伪彩色分布的变化进行统计学分析。 结果: 29例为透明细胞癌，6例为非透明细胞癌。透明细胞癌在皮髓交界期碘基图像上分别均高于非透明细胞癌，差异具有明显统计学意义（t=7.048、t=6.325，P0.05）（附图2），在实质期碘基图像上的病灶内碘浓度、病灶与腹主动脉碘浓度比值数值的差别无统计学意义（t=5.294、t=4.35，P0.05）。 结论: 双能量CT碘分布图像可以提供更直观的肿瘤强化的信息。
[Abstract]:Part one the application of the second generation dual-source CT virtual plain scan in renal space occupying objective: to investigate the clinical value of the second generation dual-source CT virtual plain-scan (VNC) in renal space-occupying lesions. Methods: routine CT plain scan and dual energy CT enhanced scan were performed in 52 patients with renal space occupying lesions. Virtual plain scan (VNC) images were obtained by liverVNC. The image quality and lesion display of VNC and conventional plain scan were evaluated by two physicians. The average CT value, SNR and radiation dose of bilateral renal lesions were measured and compared. Results: VNC images completely met the requirements of diagnosis, and there was no significant difference compared with conventional plain scan (P0.05). The volume of calcified foci in 3 cases was smaller than that in conventional plain scan on VNC. There was no significant difference between the average CT value of VNC measured and the conventional plain scan (P0.05). T-test was used to compare the images of VNC and conventional plain scan in renal parenchyma, psoas major muscle, aorta and kidney. The (VNC) SNR of virtual plain scan was slightly lower than that of conventional plain scan (P0.05). The effective doses of DLP, in single phase of virtual plain scan were 464.50 卤207.37mGy / cm and 6.96 卤3.11mSvrespectively, which were lower than those of conventional plain scan (640.94 卤195.26mGy / cm, 9.16 卤2.92mSvv, t = 4.842, 2.588, P < 0.05). Conclusion: the second generation dual-source CT can provide high-quality virtual images with significantly lower radiation dose for space-occupying lesions of the kidney. The second part is the application of dual-source CT dual-energy imaging in renal malignant space-occupying. Objective: to explore the application value of dual-energy CT dual-energy scanning iodine imaging in renal malignant space occupying. Methods: 35 cases of renal cell carcinoma confirmed by pathology were retrospectively analyzed. The iodine concentration of abdominal aorta and the ratio of lesion to aortic iodine concentration were measured in the junctional and parenchyma phases of renal tumors. The changes of iodine pseudo-color distribution between clear cell carcinoma and non-transparent cell carcinoma were analyzed statistically. Results: 29 cases were clear cell carcinoma and 6 cases were non-transparent cell carcinoma. The iodine concentration in the solid-phase iodine-based images of clear cell carcinoma was significantly higher than that in non-transparent cell carcinoma (t = 7.048, t = 6.325, P 0.05) (figure 2), and the iodine concentration of the lesions in solid phase was significantly higher than that in non-transparent cell carcinoma (t = 7.048, t = 6.325, P < 0.05). There was no significant difference in iodine concentration ratio between lesion and abdominal aorta (t = 5.294, t = 4.35, P0.05). Conclusion: dual energy CT iodine distribution images can provide more intuitive information of tumor enhancement.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.7
本文编号：2467040
[Abstract]:Part one the application of the second generation dual-source CT virtual plain scan in renal space occupying objective: to investigate the clinical value of the second generation dual-source CT virtual plain-scan (VNC) in renal space-occupying lesions. Methods: routine CT plain scan and dual energy CT enhanced scan were performed in 52 patients with renal space occupying lesions. Virtual plain scan (VNC) images were obtained by liverVNC. The image quality and lesion display of VNC and conventional plain scan were evaluated by two physicians. The average CT value, SNR and radiation dose of bilateral renal lesions were measured and compared. Results: VNC images completely met the requirements of diagnosis, and there was no significant difference compared with conventional plain scan (P0.05). The volume of calcified foci in 3 cases was smaller than that in conventional plain scan on VNC. There was no significant difference between the average CT value of VNC measured and the conventional plain scan (P0.05). T-test was used to compare the images of VNC and conventional plain scan in renal parenchyma, psoas major muscle, aorta and kidney. The (VNC) SNR of virtual plain scan was slightly lower than that of conventional plain scan (P0.05). The effective doses of DLP, in single phase of virtual plain scan were 464.50 卤207.37mGy / cm and 6.96 卤3.11mSvrespectively, which were lower than those of conventional plain scan (640.94 卤195.26mGy / cm, 9.16 卤2.92mSvv, t = 4.842, 2.588, P < 0.05). Conclusion: the second generation dual-source CT can provide high-quality virtual images with significantly lower radiation dose for space-occupying lesions of the kidney. The second part is the application of dual-source CT dual-energy imaging in renal malignant space-occupying. Objective: to explore the application value of dual-energy CT dual-energy scanning iodine imaging in renal malignant space occupying. Methods: 35 cases of renal cell carcinoma confirmed by pathology were retrospectively analyzed. The iodine concentration of abdominal aorta and the ratio of lesion to aortic iodine concentration were measured in the junctional and parenchyma phases of renal tumors. The changes of iodine pseudo-color distribution between clear cell carcinoma and non-transparent cell carcinoma were analyzed statistically. Results: 29 cases were clear cell carcinoma and 6 cases were non-transparent cell carcinoma. The iodine concentration in the solid-phase iodine-based images of clear cell carcinoma was significantly higher than that in non-transparent cell carcinoma (t = 7.048, t = 6.325, P 0.05) (figure 2), and the iodine concentration of the lesions in solid phase was significantly higher than that in non-transparent cell carcinoma (t = 7.048, t = 6.325, P < 0.05). There was no significant difference in iodine concentration ratio between lesion and abdominal aorta (t = 5.294, t = 4.35, P0.05). Conclusion: dual energy CT iodine distribution images can provide more intuitive information of tumor enhancement.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.7
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