高温高湿环境犬肢体火器伤后超氧化物歧化酶和丙二醛含量的变化

发布时间：2018-03-04 21:17

本文选题：高温高湿环境　切入点：火器伤　出处：《第一军医大学学报》2002年04期 　论文类型：期刊论文

【摘要】：目的探讨高温高湿环境下肢体火器伤后组织脂质过氧化与抗氧化酶变化的规律。方法将犬随机分为常温常湿组、热习服组、高温高湿组,分别在致伤前及火器伤后1、3、4、6、8、10、14、18、24h检测外周血和伤道骨骼肌中超氧化物歧化酶(SOD)和丙二醛(MDA)含量。结果(1)每组SOD、MDA的含量在伤后14h内呈正相趋势;(2)高温高湿组中MDA含量开始升高和其峰值的时间点提前,分别为3h和6h,峰值显著高于其他两组(P0.05),SOD的含量则相反;(3)热习服组SOD含量较高温高湿组升高;(4)三组14h后SOD、18h后MDA含量无差异。结论高温高湿火器伤可使机体内脂质过氧化反应增强,热习服则明显减低这种作用。
[Abstract]:Objective to investigate the high temperature and high humidity environment and lower limb firearm injury tissue lipid peroxidation and antioxidant enzymes after changes. Methods dogs were randomly divided into normal temperature group and heat acclimatization group, high temperature and high humidity in the injury group, respectively before and after injury 1,3,4,6,8,10,14,18,24h detection in peripheral blood and skeletal muscle injury superoxide dismutase (SOD) and malondialdehyde (MDA) content. Results (1) SOD in each group, the content of MDA after injury is positively correlated with the trend of 14h; (2) the high temperature and high humidity in group MDA was increased and the peak time in advance, respectively 3H and 6h, the peak was higher than the other two groups (P0.05), SOD was on the contrary; (3) heat acclimatization group compared with high temperature and high humidity content of SOD group increased; (4) the three groups after 14h SOD, 18h MDA content showed no difference. Conclusion firearm injury of high temperature and high humidity can make the body lipid peroxidation, heat acclimatization is obviously lower this role.

【作者单位】：第一军医大学南方医院创伤骨科第一军医大学南方医院创伤骨科第一军医大学南方医院创伤骨科第一军医大学南方医院创伤骨科
【基金】：全军九五医药卫生杰出中青年基金(98J004)
【分类号】：R82

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