沙林中毒复合腹部穿透伤的初步实验研究

发布时间：2018-04-06 03:18

本文选题：沙林　切入点：溺水　出处：《中国药理学与毒理学杂志》2003年04期

【摘要】：目的　本实验通过兔神经毒沙林中毒复合火器腹部穿透伤、落海溺水等伤情的研究 ,为临床正确处理化学战剂复合伤提供理论依据。方法　实验分正常、中毒对照、中毒 +腹部伤、中毒 +腹部伤 +中毒急救、中毒 +腹部伤 +中毒急救 +手术、中毒 +腹部伤 +溺海水、中毒 +腹部伤 +溺海水 +中毒急救、中毒 +腹部伤 +溺海水 +中毒急救 +手术共 8组。腹部伤用手枪致穿透伤 ,神经毒沙林 5 5 μg·kg- 1im中毒 ,神经毒急救针肌注。观察 2 4h伤情、存活率及病理变化。结果　未经中毒急救的动物均于 15min内死亡 ,经中毒急救未手术的动物于 4 0min后死于腹腔出血休克 ,两组经手术治疗动物
[Abstract]:Objective to provide a theoretical basis for the correct treatment of chemical warfare agent compound injury in clinic by studying the injury of nerve toxin sarin poisoning combined with firearm penetrating injury and drowning at sea.Methods the experiment was divided into normal, toxic control, poisoning abdominal injury, poisoning abdominal injury, first aid operation of poisoning abdominal injury, poisoning abdominal injury drowning seawater.There were 8 groups of first aid for poisoning abdominal injury drowning seawater poisoning and poisoning abdominal injury drowning seawater poisoning.The abdominal wound was perforated by pistol, the neurotoxin sarin was poisoned by 55 渭 g kg- 1im, and the neurotoxic first aid needle was injected intramuscularly.24 h injury, survival rate and pathological changes were observed.Results all the animals without first aid of poisoning died in 15min, and the animals without operation died of intraperitoneal hemorrhage shock after 4 0min of poisoning first aid. Two groups of animals were treated by operation.
【作者单位】：解放军第101医院外科解放军第101医院外科第二军医大学海医系第二军医大学海医系军事医学科学院毒物药物研究所解放军307医院军事医学科学院毒物药物研究所
【分类号】：R82

【相似文献】