吸氧排氮对家兔氮排出量及减压气泡形成的影响

发布时间：2018-05-01 04:14

本文选题：吸氧排氮 + 氮排出量　；参考：《第四军医大学学报》2003年20期

【摘要】：目的 :定量分析不同吸氧排氮方案时家兔的吸氧排氮效率 ,为制定我国航天员出舱活动吸氧排氮方案提供理论依据 .方法 :2 4只家兔随机分为对照组、吸氧排氮 30 ,6 0和1 2 0min组 4组 .麻醉后行机械通气 ,分别吸氧排氮 0 ,30 ,6 0和 1 2 0min ,收集呼出气 ,定量分析不同吸氧排氮时间的氮排出量 ,并用超声多普勒检测低压舱上升至 1 1 0 0 0米停留 30min的气泡产生情况 .结果 :在吸氧排氮的前 5min ,呼出气氮体积分数和氮排出量降低幅度最大 (约 93% ) ,之后随着吸氧排氮时间的延长逐渐缓慢降低 ;累积气泡数随着吸氧排氮时间的延长而减少 ,吸氧排氮 6 0和 1 2 0min组家兔累积气泡数较对照组显著减少 (P 0 .0 1 ) ,累积气泡数与吸氧排氮时间呈负相关 (r =- 0 .6 3,P 0 .0 1 ) .结论 :吸氧排氮过程的特点为先快后慢 ,吸氧排氮 6 0和 1 2 0min可显著减少高空减压时气泡的产生
[Abstract]:Objective: to quantitatively analyze the nitrogen and oxygen absorption efficiency of rabbits with different oxygen and nitrogen emission schemes, and to provide a theoretical basis for drawing up a plan of oxygen and nitrogen removal for Chinese astronauts. Methods Twenty four rabbits were randomly divided into four groups: control group, 30 0min group and 12 0min group. After anesthesia, mechanical ventilation was carried out, and the nitrogen excretion was collected and exhaled for 0 ~ 30 min and 12 0min, respectively, and the amount of nitrogen excretion was quantitatively analyzed at different time of oxygen and nitrogen excretion. Ultrasonic Doppler was used to detect the bubble formation of the low pressure chamber rising to 11000m and staying at 30min. Results: in 5min, the volume fraction of exhaled nitrogen and the amount of nitrogen excreted by exhalation were the largest (about 93%), and then decreased slowly with the prolongation of the time of oxygen uptake and excretion of nitrogen. The cumulative bubble number decreased with the prolongation of oxygen and nitrogen excretion time. The cumulative bubble number of rabbits in 60 and 12 0min groups decreased significantly compared with the control group (P0. 01). There was a negative correlation between the cumulative bubble number and the time of nitrogen uptake. Conclusion: the process of oxygen absorption and nitrogen removal is fast first and then slow, and oxygen emission 60 and 12 0min can significantly reduce the bubble formation during high altitude decompression.
【作者单位】：第四军医大学航空航天医学系航空航天生物动力学教研室第四军医大学航空航天医学系航空航天生物动力学教研室第四军医大学航空航天医学系航空航天生物动力学教研室第四军医大学航空航天医学系航空航天生物动力学教研室第四军医大学航空航天医学系航空航天生物动力学教研室上海交通大学潜水生理研究所
【分类号】：R852.16

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