饮用加银水对尾吊大鼠脂质代谢的影响

发布时间：2018-05-04 19:08

本文选题：失重模拟 + 加银水　；参考：《航天医学与医学工程》2005年03期

【摘要】：目的研究饮用加银水对尾吊模拟失重大鼠红细胞膜流动性、血脂和血管内皮细胞的影响。方法30只SD雄性大鼠随机分为地面对照组(GC组)、模拟失重对照组(SC组)和模拟失重饮用0.20mg/L加银水组(SS组),实验期21d。观察大鼠血脂指标、红细胞膜流动性以及脱落循环内皮细胞数量的变化。结果SC组大鼠血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)水平、HDLC/TC比值以及红细胞膜流动性低于GC组,LDL-C(低密度脂蛋白胆固醇)/HDL-C比值和脱落循环内皮细胞数量高于GC组。SS组和SC组比较,SS组大鼠血清TC、LDL-C和LDLC/HDL-C比值增高,HDL-C/T
[Abstract]:Objective to study the effects of drinking silver water on erythrocyte membrane fluidity, blood lipid and vascular endothelial cells (VEC) in rats with tail suspension simulated weightlessness. Methods Thirty Sprague-Dawley male rats were randomly divided into ground control group (GC group), simulated weightlessness control group (SC group) and simulated weightlessness drinking 0.20mg/L plus silver water group (SS group) for 21 days. The changes of lipid index, erythrocyte membrane fluidity and the number of exfoliated circulatory endothelial cells in rats were observed. Results in SC group, the levels of TC, TG, HDL-C, HDLC / TC and erythrocyte membrane fluidity were lower than those in GC group (LDL-C) and the number of shedding circulating endothelial cells (ECs) and the ratio of LDL-C (low density lipoprotein cholesterol / HDL-C / HDL-C) was lower than that in GC group. Compared with GC group, SS group and SC group, the ratio of serum TCU LDL-C and LDLC/HDL-C in SS group was higher than that in GC group and SC group.
【作者单位】：中国农业大学生物学院航天医学工程研究所航天医学工程研究所航天医学工程研究所航天医学工程研究所中国农业大学生物学院
【基金】：中国载人航天工程项目资助
【分类号】：R851.8

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