冲击波暴露后豚鼠耳蜗基底膜撕裂伤

发布时间：2018-05-23 07:28

本文选题：基底膜 + 耳蜗　；参考：《第三军医大学学报》2006年17期

【摘要】：目的探讨爆炸冲击波和实验性冲击波负压引起耳蜗基底膜机械损伤的组织病理学特点。方法将豚鼠暴露于爆炸冲击波和实验性冲击波负压后,分别应用火棉胶包埋组织切片技术和基底膜硬铺片技术,于光学显微镜下观察。结果爆炸冲击波和实验性冲击波负压暴露后8～24h即可见基底膜外毛细胞大部分缺失。当爆炸冲击波超压峰值达到121kPa和实验性冲击波负压峰值达到-78.4kPa时,分别发现穿透基底膜全层的位于第二转的横形及纵形机械性撕裂伤,横形撕裂伤穿透基底膜全层,从内毛细胞内侧直至第三排外毛细胞外侧;纵形撕裂形状不规则,长度相当于与其相邻的10个内毛细胞空间位置,宽度累及第二、三排外毛细胞区,一端累及内毛细胞区。结论较
[Abstract]:Objective to investigate the histopathological features of mechanical injury of cochlear basement membrane induced by blast shock wave and experimental shock wave negative pressure. Methods the guinea pigs were exposed to blast shock wave and experimental shock wave respectively. The technique of tissue section embedded with sponges and hard lamination of basement membrane were used to observe under optical microscope. Results most of the hair cells were absent from the basement membrane at 8h after blast shock wave and experimental shock wave negative pressure exposure. When the explosion shock wave overpressure peak reached 121kPa and the experimental shock wave negative pressure peak reached -78.4 KPA, the transverse and longitudinal mechanical laceration through the whole layer of the basement membrane was found, and the transverse tear wound penetrated the whole basement membrane layer, respectively. From the medial side of the inner hair cell to the outer part of the third outer hair cell, the shape of the longitudinal tear is irregular, the length of the inner hair cell is equal to the space position of the 10 inner hair cells adjacent to it, the width of the outer hair cell zone of the second and third lines is involved, and the inner hair cell area is involved at one end. Conclusion comparison
【作者单位】：第三军医大学大坪医院野战外科研究所耳鼻咽喉-头颈外科第三军医大学大坪医院野战外科研究所耳鼻咽喉-头颈外科第三军医大学大坪医院野战外科研究所第四研究室第三军医大学大坪医院野战外科研究所第四研究室第三军医大学大坪医院野战外科研究所耳鼻咽喉-头颈外科第三军医大学大坪医院野战外科研究所第四研究室第三军医大学大坪医院野战外科研究所第四研究室第三军医大学大坪医院野战外科研究所第四研究室
【分类号】：R764;R82

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