远航对舰艇官兵细胞免疫功能和营养状况的影响

发布时间：2018-07-17 00:50

【摘要】：目的探讨远航对舰艇官兵免疫功能和营养状况的影响。方法用流式细胞仪和日立模块式7600全自动血生化分析仪对173名舰艇官兵远航前后T、B、NK淋巴细胞亚群(包括CD3+、CD3+CD4+、CD3+CD8+、CD4+/CD8+、CD3-CD19+和CD3-CD56+等6项免疫指标)和血清总蛋白(TP)、白蛋白(ALB)、葡萄糖(Glu)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白A2(ApoA2)、载脂蛋白B(ApoB)、载脂蛋白C2(ApoC2)、载脂蛋白C3(ApoC3)、载脂蛋白E(ApoE)、脂蛋白a[LP(a)]及血清铁(Fe2+)、总铁结合力(TIBC)、血红蛋白(Hb)、钾(K+)、钠(Na+)、氯(Cl-)、钙(Ca2+)、镁(Mg2+)等指标进行了检测。结果与航前比较,舰艇官兵CD3+淋巴细胞、CD3+CD4+淋巴细胞、CD4+/CD8+均显著升高(P0.05),CD3+CD8+淋巴细胞显著降低(P0.05)。Glu、ApoC2水平显著升高(P0.01),ApoA2水平升高(P0.05),TC、LDC-C、ApoB、LP(a)水平显著降低(P0.01);总铁结合力水平升高(P0.05),TP、ALB、Hb水平显著降低(P0.01),血清Fe2+水平降低(P0.05),Mg2+水平升高(P0.05),Na+、Ca2+水平显著降低(P0.01)。结论远航期间舰艇官兵免疫力提高,白蛋白和血清Fe2+、Na+、Ca2+水平降低,应给予及时补充。
[Abstract]:Objective to investigate the effect of long voyage on immune function and nutritional status of warship officers and soldiers. Methods using flow cytometry and Hitachi module-type 7600 automatic blood biochemistry analyzer, the lymphocyte subsets (including CD3, CD3, CD3, CD3, CD3CD8, CD4 / CD8, CD3-CD19, CD3-CD56, and so on) and serum total protein (TP) were measured in 173 naval officers and soldiers before and after the voyage. Albumin (ALB), glucose (Glu), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (ApoA1), apolipoprotein A2 (ApoA2), apolipoprotein B (ApoB), apolipoprotein C2 (ApoC2), apolipoprotein C3 (ApoC3), apolipoprotein E (ApoE), egg fat. Serum iron (Fe 2), total iron binding capacity (TIBC), hemoglobin (HB), potassium (K), sodium (Na), chlorine (Cl-), calcium (Ca 2), magnesium (mg 2) were determined. The results were compared with those before the voyage. The CD4 / CD8 ratio of CD3 lymphocytes and CD3 CD4 lymphocytes were significantly increased (P0.05) and CD3 CD8 lymphocytes were significantly decreased (P0.05). (P0.01) the level of ApoA2 was significantly increased (P0.01). (P0.05) the level of TCL-CG-ApoBU (a) decreased significantly (P0.01), the level of total iron binding force (P0.05) decreased significantly (P0.01), the level of serum ApoA2 decreased significantly (P0.01), the level of total iron binding force (P0.05) decreased significantly (P0.01), and the level of serum ApoA2 decreased significantly (P0.01). The level of serum Fe 2 decreased (P0.05) and the level of Mg2 increased (P0.05) the level of Ca 2 decreased significantly (P0.01). Conclusion during the long voyage, the immunity of naval officers and soldiers was improved, and the levels of albumin and serum Fe 2 + Na + Ca 2 + were decreased, which should be replenished in time.
【作者单位】：
【基金】：军队“十一五”专项项目课题(06Z053)
【分类号】：R82

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